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Can a heart drug save lives in septic shock? new trial aims to find out.

NCT ID NCT04031573

First seen Apr 07, 2026 · Last updated Jun 09, 2026 · Updated 8 times

Summary

This study tests a drug called ivabradine in 429 adults with septic shock, a life-threatening condition where infection causes dangerously low blood pressure. Many patients develop a fast heart rate, which can worsen outcomes. Ivabradine slows the heart without weakening its pumping strength, unlike standard beta-blockers. The goal is to see if controlling heart rate this way reduces deaths at 28 days.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Henri Mondor Hospital

    Créteil, 94000, France

Conditions

The condition(s) this trial relates to.

toxic shock syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.