Simple painkiller before surgery may cut morphine use
NCT ID NCT07368790
First seen Feb 01, 2026 · Last updated Jun 23, 2026 · Updated 19 times
Summary
This study looked at whether giving paracetamol (a common pain reliever) before a total abdominal hysterectomy could lower the amount of morphine needed after surgery. Forty women aged 30-50 took part. Half received IV paracetamol before surgery, and the other half received a placebo (salt water). The researchers measured how much morphine each group used and their pain scores over 24 hours.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Queen Savang Vadhana Memorial Hospital, Thai Red Cross Society, Jermjomphon street, Chonburi, 20110,
Chon Buri, Thailand
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
paracetamol (acetaminophen)
What this could lead to
If it works, this could show a simple way to reduce strong painkiller use after surgery.
What could go wrong
This is a small, completed trial with only 40 participants, so results may not apply to everyone. Paracetamol may not significantly reduce morphine needs.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.