Could a simple painkiller before surgery cut stronger drug use?

NCT ID NCT07368790

Completed Symptom relief Sponsor: Queen Savang Vadhana Memorial Hospital, Thailand Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether giving paracetamol (acetaminophen) through an IV before a total abdominal hysterectomy reduces the need for morphine afterward. Forty women aged 30-50 took part. The goal was to see if they used less morphine and felt less pain in the first 24 hours after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: paracetamol (acetaminophen)
What this could lead to: If it works, this could mean less morphine needed after hysterectomy, reducing side effects like nausea or drowsiness.
What could go wrong: This is a small, completed trial with only 40 participants. The results may not apply to everyone, and paracetamol might not reduce morphine use significantly.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

POSTOPERATIVE PAIN

Contacts and locations

Locations

Queen Savang Vadhana Memorial Hospital, Thai Red Cross Society, Jermjomphon street, Chonburi, 20110,

Chon Buri, Thailand

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