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Mountain iron mystery: new study tracks how altitude changes your Body's iron needs

NCT ID NCT07142590

Knowledge-focused Sponsor: Diego Moretti Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at how living at high altitudes affects the body's iron levels. Iron is important for carrying oxygen in the blood, and high altitudes may change how much iron you absorb and lose. Researchers will give 120 healthy adults a special iron tracer and track it over a year to learn more. The goal is to create better iron recommendations for people living at high altitudes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 120 people

The number the study aims to enrol. It can still change while the study runs.

Started

Aug 2025

Expected to finish

Feb 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 45 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Females and males aged 18-45 y * BMI: 18 to 25 kg/m2 * Body weight \<70 kg for females, \<85 kg for males * Plasma ferritin \>25 µg/L * Signed informed consent Exclusion Criteria: * Hb \<12 g/dL (females), Hb \<13 g/dL (males), corrected for altitude using the 2024 WHO guidance values for hemoglobin adjustments * Inflammation (CRP \> 5 mg/L)1 * Plasma ferritin \>150 µg/L for females and \>200 µg/L for males * Chronic disease known to affect iron metabolism * Chronic medications (except for oral contraceptives) * Pregnancy (tested at screening) or intention to become pregnant during the course of the study * Lactation * High physical activity (MET-min/week \> 3000 calculated according to the IPAQ, short version, administered at the screening) * Difficulty with blood withdrawal * Earlier participation in a study using stable iron isotopes or participation in any clinical study within the last 30 days * Smoking * Blood donation, blood transfusion or significant blood loss (more than 400 mL) over the past 6 months * Intention to regularly donate blood during the 2 years duration of the study * No residence in the respective location/altitude for at least the last 2 years * No intention to reside in the respective location/altitude at least for the next 2 years * Participants who are planning to spend an extended period (\>12 weeks) at a different altitude from their residence location * Spending more than 2 nights per week at a different location from residence location * Inability to understand the information sheet and the informed consent form due to cognitive or language reasons

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Conditions

The condition(s) this trial relates to.

altitude sickness

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Altitude Iron absorption Iron requirements

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Fernfachhochschule Schweiz (FFHS)

    RECRUITING

    Zurich, Canton of Zurich, 8005, Switzerland

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