Breathing therapy may improve lung function in ventilated kids
NCT ID NCT06836050
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This completed study looked at whether a breathing treatment called Intrapulmonary Percussive Ventilation (IPV) can improve lung stiffness (compliance) in critically ill children who are on breathing machines. Researchers measured lung function before and after one IPV session in 30 children. The study did not test a new drug or device; it simply collected data from standard care to see if IPV helps lungs become more flexible.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Intrapulmonary Percussive Ventilation (IPV)
- What this could lead to
- If IPV is shown to improve lung compliance, it could support its use as a standard therapy to help children on ventilators breathe more easily.
- What could go wrong
- This is a small, completed observational study (30 children) that only measured short-term effects. It does not test long-term outcomes or prove IPV works better than other methods.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
-
30 people
The number who actually took part.
- Started
-
Jan 2025
- Finished
-
Mar 2026
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
A heterogeneous population of pediatric patients \<18 years old requiring conventional invasive mechanical ventilation and receiving IPV. We will also specifically identify and observe patients who meet criteria for Pediatric Acute Respiratory Distress Syndrome (PARDS) and compare the effects of IPV on lung compliance in this group relative to those without PARDS.
- Ages
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0 days to 18 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * ≤18 years old on conventional intermittent mandatory ventilation in the PICU that the physician deems is a candidate for IPV Exclusion Criteria: * The inability to accurately obtain ventilator measurements
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Cohen Children's Medical Center
New Hyde Park, New York, 11040, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- New study aims to find best breathing support for kids with ARDS
- New computer tool aims to keep Kids' diaphragms strong on ventilators