Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

Could a Blood-Derived injection help heal gums after deep cleaning?

NCT ID NCT07029035

Disease control Sponsor: Saglik Bilimleri Universitesi Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether injecting a substance made from a patient's own blood, called injectable platelet-rich fibrin (i-PRF), can improve gum healing after a deep dental cleaning. Twenty adults with advanced gum disease received i-PRF on one side of their mouth and a saltwater placebo on the other. Researchers measured gum pocket depth, attachment levels, and healing markers in gum fluid over three months to see if i-PRF boosts recovery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
injectable platelet-rich fibrin (i-PRF)
What this could lead to
If it works, this could point toward a new, natural treatment to improve gum healing after standard deep cleaning for periodontitis.
What could go wrong
This is a very small, early study (20 people) that only compared two sides of the mouth. Results may not apply to everyone, and the treatment may not show significant benefit over standard care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

20 people

The number who actually took part.

Started

Dec 2023

Finished

May 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Being diagnosed with Stage 3 Grade B periodontitis * Being between the ages of 18-65 Exclusion Criteria: * Smoking * Having a systemic disease * Taking any medication * Being pregnant or breastfeeding * Having received chemotherapy, radiotherapy or immunosuppressant treatments * Having received periodontal treatment in the last 6 months * Having used antibiotics in the last 6 months

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Periodontitis stage III are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

periodontitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Periodontitis stage III

Contacts and locations

Locations

  • Saglik Bilimleri Universitesi Gulhane Dis Hekimligi Fakultesi

    Ankara, Turkey (Türkiye)

More trials for these conditions

Other studies related to the condition(s) this trial covers.