Could a Blood-Derived injection help heal gums after deep cleaning?
NCT ID NCT07029035
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether injecting a substance made from a patient's own blood, called injectable platelet-rich fibrin (i-PRF), can improve gum healing after a deep dental cleaning. Twenty adults with advanced gum disease received i-PRF on one side of their mouth and a saltwater placebo on the other. Researchers measured gum pocket depth, attachment levels, and healing markers in gum fluid over three months to see if i-PRF boosts recovery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
injectable platelet-rich fibrin (i-PRF)
What this could lead to
If it works, this could point toward a new, natural treatment to improve gum healing after standard deep cleaning for periodontitis.
What could go wrong
This is a very small, early study (20 people) that only compared two sides of the mouth. Results may not apply to everyone, and the treatment may not show significant benefit over standard care.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Saglik Bilimleri Universitesi Gulhane Dis Hekimligi Fakultesi
Ankara, Turkey (Türkiye)