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New study aims to reduce unnecessary pancreatic surgery with smarter biomarkers

NCT ID NCT06694792

Knowledge-focused Sponsor: IRCCS San Raffaele Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is looking for new biomarkers to tell which pancreatic cysts (IPMNs) are likely to become cancerous. Researchers will analyze genetic, metabolic, and lifestyle data from 800 patients to develop a risk score. The goal is to help doctors decide who truly needs surgery and who can safely avoid it.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could give doctors a new tool to predict which pancreatic cysts are dangerous, helping avoid unnecessary surgery.
What could go wrong
This is an observational study, not a treatment trial. It is still early, and the biomarkers found may not prove accurate enough for routine use.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 800 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jan 2025

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Adult patients with diagnosis of IPMN

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adult (age \>18 years) patients with a diagnosis of IPMN undergoing and not undergoing surgery * All patients will sign the informed consent For the retrospective patients: * confirmed IPMN diagnosis * signed informed consent for samples biobanking and study participation Exclusion Criteria: * Patients \< 18 years of age * Patients who are not able to supply an informed consent

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Conditions

The condition(s) this trial relates to.

pancreas disorder Pancreatic Intraductal Neoplasms pancreatic intraductal papillary-mucinous neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Ipmn, pancreatic

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • San Raffaele Hospital

    RECRUITING

    Milan, MI, 20132, Italy

More trials for these conditions

Other studies related to the condition(s) this trial covers.