New study aims to uncover why some patients develop hernias after major cancer surgery
NCT ID NCT07451483
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study reviews medical records of 500 adults who had cytoreductive surgery (with or without heated chemotherapy) for advanced abdominal cancers. The goal is to find out how often incisional hernias occur and what patient or surgical factors increase the risk. Researchers hope the findings will lead to better prevention and treatment strategies.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this study could help doctors better predict and prevent incisional hernias in patients undergoing this complex surgery, improving recovery and quality of life.
- What could go wrong
- This is a retrospective observational study, so it can show links but not prove cause and effect. Results may not apply to all hospitals or patient groups.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 500 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jan 2026
- Expected to finish
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Mar 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
This single-center quantitative retrospective study conducted at the Institut Jules Bordet includes patients who underwent cytoreductive surgery ± HIPEC for pseudomyxoma peritonei, colorectal or ovarian peritoneal carcinomatosis between January 1, 2010, and December 31, 2024.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * All adult patients (≥18 years) who underwent CRS +/- HIPEC for PMP, colorectal and ovarian PC between 01 January 2010 and 31 December 2024. Exclusion Criteria: * Patients with a prior history of ventral hernia at the planned incision site. * Patients undergoing CRS +/- HIPEC for primary cancer other than PMP, colorectal and ovarian PC. * Patients with incomplete medical records preventing data extraction. * Patients lost to follow-up within one year of surgery.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Jules Bordet Institute
RECRUITINGAnderlecht, Brussels Capital, 1070, Belgium
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Fish oil drink before surgery may cut complications, tiny study hints
- Single dose of esketamine during surgery may ward off Post-Op depression in ovarian cancer patients
- Heated chemo during surgery may extend life for Drug-Resistant ovarian cancer