Fish oil drink before surgery may cut complications, tiny study hints
NCT ID NCT07478432
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This pilot study tests whether drinking an omega-3-enriched nutritional supplement for 21 days before surgery can reduce complications in people with abdominal cancer. 28 patients will be randomly assigned to get either the omega-3 drink or a standard supplement. Researchers will track infections, hospital stay length, and other recovery measures.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Omega-3 fatty acids (in an oral nutritional supplement)
- What this could lead to
- If it works, this could point toward a simple nutritional drink that helps people recover better after major cancer surgery.
- What could go wrong
- This is a very small pilot study with only 28 people, so results may not be reliable or apply to everyone. The supplement might not reduce complications at all.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 28 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Apr 2026
An estimate. Start dates often move.
- Expected to finish
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Oct 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age \> 18 years * Diagnosis of peritoneal carcinomatosis from a non-gynecological primary neoplasm * Patients who must undergo cytoreductive surgery and HIPEC * Signed informed consent form Exclusion Criteria: * Patients with an enterocutaneous fistula * Patients with known food allergies * Age \< 18 years * Patients with severe organ damage (e.g., kidney failure, liver failure) * Refusal to sign the informed consent form
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Get notified about this study
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Clinical Nutrition Unit, Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Roma, 00168, Italy
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Chemotherapy sprayed directly into the abdomen: a new attack on stubborn cancers
- New radiation technique targets stomach and ovarian cancer spread without surgery
- Tiny blood vessel coating may hold key to better surgery monitoring
- New chemo spray aims to ease suffering from abdominal cancer spread
- New chemo spray shows promise for Hard-to-Treat abdominal cancers
- Could chemo around surgery beat cancer spread in the belly?