Better brain zaps: new study hopes to boost depression treatment
NCT ID NCT03851380
First seen Apr 24, 2026 · Last updated Jun 20, 2026 · Updated 9 times
Summary
This study tests whether using MRI scans to guide transcranial magnetic stimulation (rTMS) leads to better outcomes for people with depression than the usual scalp-based method. It involves 54 participants and also offers home-based brain stimulation and therapy for those with COVID-related stress. The goal is to improve targeting accuracy and quality of life.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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VA Palo Alto Health Care System, Palo Alto, CA
Palo Alto, California, 94304-1207, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
transcranial magnetic stimulation (rTMS) and transcranial electrical stimulation (tES)
What this could lead to
If successful, this could make rTMS therapy more effective for depression by improving targeting accuracy, and offer a home-based brain stimulation option for stress.
What could go wrong
This is a small, early-stage study (54 participants) focused on measuring accuracy and feasibility, not yet proving clinical benefit. Results may not apply to all patients.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.