Your own tooth could be the best bone graft for dental implants
NCT ID NCT07324083
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether using a patient's own extracted tooth as a bone graft (AMDG) works better than a synthetic material (β-TCP) or no graft at all for preserving the jawbone after tooth removal. Twenty-two adults who needed a maxillary premolar pulled received one of the three treatments, then got a dental implant six months later with a crown placed within two days. The researchers measured bone changes, implant stability, and gum health over two years to see which approach gave the best foundation for the implant.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Autogenous mineralized dentin graft (AMDG) or beta-tricalcium phosphate (β-TCP)
- What this could lead to
- If successful, this could show that using a patient's own tooth as a bone graft is as good as or better than synthetic materials for preserving the jawbone before placing dental implants.
- What could go wrong
- This is a small, completed trial with only 22 participants, so results may not apply to everyone. The approach requires a healthy healing response and may not work for patients with poor bone quality or heavy smoking habits.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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22 people
The number who actually took part.
- Started
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Jan 2023
- Finished
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Aug 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria * Adults aged 18 years or older * Patients requiring extraction of a maxillary premolar tooth * Adequate bone height to allow delayed implant placement * Good oral hygiene and compliance with follow-up visits * Ability to understand the study procedures and provide written informed consent Exclusion Criteria * Presence of uncontrolled systemic diseases that could affect bone healing * History of radiotherapy to the head and neck region * Heavy smoking * Active infection or untreated periodontal disease at the extraction site * History of bisphosphonate or other antiresorptive drug use * Poor oral hygiene or inability to comply with study protocol
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Faculty of Dentistry, Mansoura University
Al Mansurah, Egypt
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- The race to save jawbone: four socket techniques go head to head
- Your extracted tooth may become the next bone graft
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