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Heart surgery danger: unstable blood pressure linked to brain and kidney damage

NCT ID NCT07324694

Knowledge-focused Sponsor: Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Sep 04, 2026 · Updated 4 times

Summary

This study tracks 230 adults having planned heart surgery to see if unstable blood pressure during the operation raises the risk of serious problems like confusion, kidney injury, stroke, or death within 30 days. Researchers will monitor blood pressure dips and use of pressure-raising drugs. The goal is to better understand which patients are at higher risk so doctors can improve care.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this study could help doctors better manage blood pressure during heart surgery to reduce serious complications.
What could go wrong
This is an observational study, not a treatment trial. It can show links but not prove cause and effect. Results may not apply to all heart surgery patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 230 people

The number the study aims to enrol. It can still change while the study runs.

Started

Apr 2025

Expected to finish

Sep 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Adult patients undergoing elective cardiac surgery with cardiopulmonary bypass at a tertiary care university hospital.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients aged 18 years or older. * Scheduled for elective cardiac surgery (CABG, Valve replacement/repair, or combined procedures). * Surgery performed under cardiopulmonary bypass (CPB). * Preoperative sinus rhythm. * Signed informed consent form. Exclusion Criteria: * Emergency or salvage surgery. * Off-pump coronary artery bypass grafting. * Preoperative mechanical circulatory support (IABP, ECMO) requirement. * Pre-existing chronic renal failure requiring dialysis (HD/PD). * Pre-existing cognitive impairment, dementia, or history of psychiatric disorders affecting cooperation. * Pregnancy.

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Conditions

The condition(s) this trial relates to.

acute kidney injury Emergence Delirium Postoperative Complications

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Acute kidney injury Cardiac surgery Intraoperative hemodynamic instability Postoperative complication Postoperative delirium (POD)

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Gazi Yaşargil Training and Research Hospital

    RECRUITING

    Diyarbakır, Diyarbakır, 21070, Turkey (Türkiye)

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