Heart study asks: do ICDs help Low-Risk patients?

NCT ID NCT06543446

Terminated Knowledge-focused Sponsor: University of Rochester Source: ClinicalTrials.gov ↗

First seen Jan 11, 2026 · Last updated Jun 08, 2026 · Updated 23 times

Summary

This study looked at whether implantable defibrillators (ICDs) help people with heart failure and a lower risk of deadly heart rhythms live longer compared to not having an ICD. It involved over 3,000 adults with weak heart pumps. The goal was to see if the benefits of ICDs still hold in today's better-treated heart failure patients.

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Contacts and locations

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Locations

Corewell Health

Grand Rapids, Michigan, 49503, United States
Intermountain Health Care, Inc.

Salt Lake City, Utah, 84111, United States
Johns Hopkins University

Baltimore, Maryland, 21287, United States
MaineHealth

Portland, Maine, 04102, United States
Minneapolis Heart Institute Foundation

Minneapolis, Minnesota, 55407, United States
Northwell Health

New York, New York, 10075, United States
Nuvance Health Hudson Valley Cardiovascular Practice, PC

Poughkeepsie, New York, 12601, United States
Rutgers

New Brunswick, New Jersey, 08901, United States
The Valley Hospital

Paramus, New Jersey, 07652, United States
Tufts Medical Center

Boston, Massachusetts, 02111, United States
University of Alberta

Edmonton, Alberta, T6G 2B7, Canada
University of Calgary

Calgary, Alberta, T2N4Z6, Canada
University of Rochester

Rochester, New York, 14642, United States
University of Virginia Health System

Charlottesville, Virginia, 22902, United States
West Virginia University

Morgantown, West Virginia, 26506, United States

Conditions

The condition(s) this trial relates to.

Death, Sudden, Cardiac systolic heart failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEART FAILURE WITH REDUCED EJECTION FRACTION