Common painkiller may shield elderly brains after surgery
NCT ID NCT07424001
First seen Feb 28, 2026 · Last updated Jun 21, 2026 · Updated 23 times
Summary
This study tested whether giving ibuprofen before hernia surgery could prevent confusion and memory problems in older adults. 76 men aged 65-84 received either ibuprofen or a placebo before their operation. Researchers measured thinking skills, pain levels, and recovery quality for a week after surgery.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Istanbul medeniyet Universitesi Prof. Dr. Süleyman Yalçın Şehir Hastanesi
Istanbul, Kadıköy, 34710, Turkey (Türkiye)
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
ibuprofen
What this could lead to
If it works, this could point toward a simple way to protect older patients' thinking and memory after surgery.
What could go wrong
This is a small, early-phase study in only 76 men, so results may not apply to everyone. Ibuprofen can cause stomach or kidney issues in some people.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.