Simple tube coating may ease Post-Surgery throat pain
NCT ID NCT07124650
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether coating the breathing tube with either hydrocortisone ointment or lidocaine solution can lessen sore throat, hoarseness, and coughing after thyroid or parathyroid surgery. About 764 adults will be randomly assigned to one of the two treatments. Researchers will check pain and voice changes right after surgery, at 24 hours, and at 3 days to see which approach works better.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 4
Runs after approval, following long-term safety and how well the treatment works in everyday use.
- Participants
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About 764 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Sep 2025
- Expected to finish
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May 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients scheduled for elective open surgery on the thyroid/parathyroid glands with intraoperative neuromonitoring. * Age ≥18 years. * Willing and able to provide voluntary informed consent for participation in the study. Exclusion Criteria: * Pregnancy (for women of childbearing potential). * Known allergy to hydrocortisone or lidocaine. * Refusal to participate in the study.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Saint Petersburg State University Hospital
RECRUITINGSaint Petersburg, Russia
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can a new infrared camera help surgeons spot nerves and bile ducts?
- A dab of gel on the breathing tube might spare surgery patients a sore throat — a trial puts it to the test.
- Simple pressure check may spare kids from post-surgery sore throat
- Pesticide found in thyroid glands of caribbean patients
- Neck nerve block may ease Body's stress during thyroid surgery