Neck nerve block may ease Body's stress during thyroid surgery
NCT ID NCT07600580
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether a nerve block in the neck, given during thyroid surgery, can lower the body's stress response. 48 adults will be split into two groups: one gets standard anesthesia, the other gets the same plus a nerve block. Researchers will measure stress markers in blood and saliva to see if the block helps.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- levobupivacaine
- What this could lead to
- If it works, this could lead to a standard nerve block during thyroid surgery to lower stress and speed recovery.
- What could go wrong
- This is a small, early-phase study (48 people) measuring biomarkers, not direct outcomes like pain or recovery time. The block may not reduce stress meaningfully.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 4
Runs after approval, following long-term safety and how well the treatment works in everyday use.
- Participants
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About 48 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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May 2024
- Expected to finish
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Aug 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * patienets of both sexes * 18 years of age and older * ASA I or ASA II * euthyroid status * signed informed consent Exclusion Criteria: * patients who refuse to sign the informed consent form * infection at the block injection site * hypersensitivity or contraindications to the medications used in the study * hypothyroidism or hyperthyroidism at the time of surgery * presence of substernal goiter * additional surgical interventions during the procedure * history of previous neck surgery or radiation * coagulopathy * uncontrolled respiratory disease * diabetes mellitus * autoimmune disease * chronic corticosteroid therapy * smokers * pregnant women.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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University Hospital Dubrava
RECRUITINGZagreb, City of Zagreb, 10000, Croatia
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