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Promising heart rhythm fix trial halted early – only 7 patients tested

NCT ID NCT03737929

First seen Jun 15, 2026 · Last updated Jun 23, 2026 · Updated 2 times

Summary

This study aimed to see if combining surgical and catheter ablation (hybrid therapy) works better than standard catheter ablation alone for people with persistent atrial fibrillation. The trial was terminated after enrolling only 7 participants, so no meaningful conclusions can be drawn. The approach remains experimental and unproven.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • CHU Toulouse, Hôpital Rangueil

    Toulouse, 31059, France

  • Cardiology-rytmology

    Paris, France

  • Cardiology-rytmology service

    Toulouse, France

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Hybrid ablation (surgical epicardial ablation combined with percutaneous catheter ablation)

What this could lead to

If it had succeeded, this approach could have offered a more effective treatment for persistent atrial fibrillation, potentially reducing recurrence and the need for repeat procedures.

What could go wrong

The trial was terminated early with only 7 participants, so results are not reliable. Hybrid ablation also carries higher complication risks than catheter ablation alone.

Conditions

The condition(s) this trial relates to.

atrial fibrillation persistent atrial fibrillation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.