New injection could ease Post-Surgery pain without opioids
NCT ID NCT02689258
First seen Mar 05, 2026 · Last updated Jun 23, 2026 · Updated 10 times
Summary
This phase 2 trial tested two experimental drugs, HTX-011 and HTX-002, for pain relief after abdominoplasty (tummy tuck) surgery. 277 adults received an injection of the drug or a placebo. The main goal was to measure pain intensity over the first 24 hours. The study is now complete, and results will show if these drugs offer better pain control than standard care.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Study site
Phoenix, Arizona, 85023, United States
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Study site
Pasadena, California, 91105, United States
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Study site
Pasadena, Maryland, 21122, United States
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Study site
Bellaire, Texas, 77401, United States
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Study site
Houston, Texas, 77004, United States
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Study site
Houston, Texas, 77019, United States
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Study site
Houston, Texas, 77027, United States
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Study site
Plano, Texas, 75093, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
HTX-011 (bupivacaine/meloxicam injection)
What this could lead to
If it works, this could provide longer-lasting pain relief after surgery, reducing the need for opioid painkillers.
What could go wrong
This is an early phase 2 trial, so results may not confirm effectiveness. Pain relief varies by person, and side effects like nausea or injection-site reactions are possible.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.