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Scientists probe fat tissue to unlock Exercise's health secrets

NCT ID NCT06053125

Knowledge-focused Sponsor: Mayo Clinic Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This Mayo Clinic study looks at how a single session of exercise affects fat tissue in healthy adults of different ages and weights. Researchers will take small fat samples from the belly before, right after, and three hours after a 30-minute bike workout. They want to see how exercise changes immune cells and inflammation in fat, which could help explain why exercise improves health as we age or with obesity.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this study could reveal how exercise-induced changes in fat tissue improve health, potentially guiding future treatments for aging and obesity.
What could go wrong
This is a small, early-stage observational study with only 56 participants. It measures biological markers, not health outcomes, so direct benefits are uncertain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

56 people

The number who actually took part.

Started

Nov 2023

Expected to finish

Oct 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 85 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults between the ages of 18-35 OR 65-85. * BMI 18.5 kg/m2 - 40 kg/m2 * Weight stable (≥ 3 months) * Generally healthy Exclusion Criteria: * Participation in ≥ 30 minutes of structured physical activity ≥ 2 days per week. * Smoking/tobacco use. * Alcohol/substance abuse. * Pregnancy and breastfeeding. * Anemia. * Abnormal renal function. * Blood clotting disorders. * Coronary artery disease. * Uncontrolled thyroid disease. * Liver disease. * Use of medications known to influence the main outcomes of the study. * Orthopedic problems that may be aggravated by exercise. * Chronic disease at the discretion of the investigators.

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Conditions

The condition(s) this trial relates to.

Motor Activity Obesity obesity disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Healthy Obesity

Contacts and locations

Locations

  • Mayo Clinic

    Rochester, Minnesota, 55905, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.