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New hospital program aims to keep opioid patients on methadone after discharge

NCT ID NCT07568847

Disease control Sponsor: University of Colorado, Denver Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether completing methadone clinic intake during a hospital stay helps people with opioid use disorder stay connected to treatment after leaving. Researchers will compare usual care (a referral at discharge) to a program where hospital staff complete key steps like medical assessment and methadone initiation before the patient goes home. The goal is to see if this approach increases the number of people who successfully link to a methadone clinic within 7 days of discharge.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
methadone
What this could lead to
If this works, it could make it easier for people leaving the hospital to stay on methadone treatment, reducing the risk of relapse, overdose, and repeat hospital visits.
What could go wrong
This is an early implementation study, not a drug trial. Success depends on hospital staff following new workflows, and results may vary across hospitals. It does not test a new medication.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 1,440 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Oct 2026

An estimate. Start dates often move.

Expected to finish

Nov 2030

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age ≥18 years * Hospitalized with DSM-5 opioid use disorder, confirmed by clinical assessment * Eligible for methadone treatment as determined by the clinical team * Not currently enrolled in an Opioid Treatment Program (OTP) * Anticipated discharge to the community * Willing to initiate methadone and follow up at a partnering OTP Exclusion Criteria: * Current enrollment in an Opioid Treatment Program (OTP) * Planned discharge to a correctional or institutional setting that precludes OTP follow-up * Medical or psychiatric instability that precludes safe methadone initiation or completion of study procedures * Inability to provide required information for OTP intake due to impaired cognition or altered mental status

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Conditions

The condition(s) this trial relates to.

opiate dependence

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Opioid use disorder

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  2. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

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