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Housing first: a bold experiment to stop opioid addiction before it starts

NCT ID NCT04135703

Prevention Sponsor: Ohio State University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tested whether giving homeless young people (ages 18-24) a place to live plus support services could help them avoid developing opioid use disorder. 240 participants who were homeless but did not yet have opioid addiction were randomly assigned to receive either housing with prevention services or prevention services alone. Researchers tracked their opioid use over a year to see if housing made a difference.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Housing (rental assistance) plus opioid risk prevention services
What this could lead to
If successful, this could show that providing stable housing alongside prevention services helps homeless youth avoid developing opioid use disorder.
What could go wrong
This is a single completed trial with 240 participants, so results may not apply broadly. Housing alone may not be enough to prevent substance use in all youth.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

240 people

The number who actually took part.

Started

Jun 2020

Finished

May 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 24 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * ages of 18 to 24 years * meets McKinney-Vento definition of homeless * fails to meet DSM 5 criteria for Opioid Use Disorder as assessed by the SCID Exclusion Criteria: \-

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Conditions

The condition(s) this trial relates to.

substance abuse substance-related disorder opiate dependence prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Substance use

Contacts and locations

Locations

  • The Ohio State University

    Columbus, Ohio, 43210, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.