Could a headset at home boost brain recovery? new study tests tDCS for stroke, tumors, and neurodegeneration
NCT ID NCT07091396
First seen Jun 26, 2026 · Last updated Aug 20, 2026 · Updated 3 times
Summary
This study tests whether a home-based brain stimulation device (tDCS) combined with activity therapy can help improve cognitive and language problems in people with stroke, brain tumors, or neurodegenerative conditions like Parkinson's or Alzheimer's. Fifty-five participants will use the device for 20-minute sessions over two to four weeks. The goal is to see if this approach is feasible and can improve memory, speech, and quality of life.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- transcranial direct current stimulation (tDCS) device
- What this could lead to
- If it works, this could provide a convenient home-based treatment to help improve memory, language, and daily function for people with stroke, brain tumors, or neurodegenerative conditions.
- What could go wrong
- This is a small early feasibility study with only 55 participants and no control group, so results may not be generalizable. The benefits of tDCS for these conditions are still unproven.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 55 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jan 2026
- Expected to finish
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Dec 2031
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * At least 3 months after ischemic/hemorrhagic/anoxic stroke or 3 months after completion of cranial radiation or cranial surgery for treatment of primary or metastatic intracranial tumors or neurodegenerative conditions include, but are not limited to, primary progressive aphasia, corticobasal syndrome, progressive supranuclear palsy, Parkinson's disease, and Alzheimer's disease dementia. * Expected survival \>6 months * Functional impairment in the domains of language and/or cognition affecting quality of life determined by PI. * Have a legally authorized representative who is able to sign on their behalf in unable to consent for themselves (ex., individuals with aphasia). * Have a legally authorized representative who is able to sign on their behalf in unable to consent for themselves (ex., individuals with aphasia). Exclusion Criteria: * Pregnancy * Contraindication to tDCS, including metallic implanted objects. * Medical instability or inability to cooperate during the study as assessed by the treating physician to participate in the study. * Individuals with epilepsy
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Mayo Clinic in Rochester
Rochester, Minnesota, 55905, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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