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New HIV prevention shot could protect drug users

NCT ID NCT07199335

First seen Nov 01, 2025 · Last updated Jun 21, 2026 · Updated 38 times

Summary

This study is testing whether a long-acting injectable HIV prevention drug, cabotegravir, works well for people who inject drugs. One hundred adults who have injected non-prescription drugs in the past 6 months and are at risk for HIV through sex will receive the shot along with support services. Researchers will measure how many participants stick with the treatment after 7 months.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Fenway Health

    RECRUITING

    Boston, Massachusetts, 02215, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Massachusetts General Hospital

    RECRUITING

    Boston, Massachusetts, 02114, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

cabotegravir (injectable PrEP)

What this could lead to

If successful, this could provide a practical HIV prevention option for people who inject drugs, reducing new infections in this high-risk group.

What could go wrong

This is a small, early-phase feasibility study with only 100 participants, so results may not apply broadly. The drug is already approved for sexual HIV risk, but its effectiveness in this specific population is unproven.

Conditions

The condition(s) this trial relates to.

HIV infectious disease substance-related disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.