HIV-Positive hearts for HIV-Positive patients: a lifesaving match?
NCT ID NCT06659952
First seen Jan 21, 2026 · Last updated Jun 22, 2026 · Updated 23 times
Summary
This study looks at whether heart transplants from HIV-positive donors are as safe and effective for HIV-positive recipients as those from HIV-negative donors. Fifty participants with advanced heart failure and HIV will receive a heart from either an HIV-positive or HIV-negative donor, based on availability. Researchers will track survival, graft function, and serious side effects for three years after transplant.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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UT Southwestern Medical Center
RECRUITINGDallas, Texas, 75390, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
HIV-positive donor heart
What this could lead to
If successful, this could expand the donor pool for HIV-positive patients with advanced heart failure, reducing wait times.
What could go wrong
This is a small, early-stage study (50 participants) and outcomes may not apply broadly. There are unknown risks of using HIV-positive donor organs.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.