HIV-Positive hearts for HIV-Positive patients: a lifesaving experiment?
NCT ID NCT06659952
First seen Jan 21, 2026 · Last updated Jun 24, 2026 · Updated 24 times
Summary
This study looks at whether hearts from HIV-positive deceased donors are as safe and effective for HIV-positive recipients as hearts from HIV-negative donors. Fifty HIV-positive patients with advanced heart failure will receive a heart transplant, with the donor's HIV status determined by organ availability. Researchers will track survival, graft function, and serious side effects for three years after transplant.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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UT Southwestern Medical Center
RECRUITINGDallas, Texas, 75390, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
HIV-positive heart transplant
What this could lead to
If successful, this could expand the donor pool for HIV-positive patients needing heart transplants, potentially reducing wait times and saving lives.
What could go wrong
This is a small, early-stage study with only 50 participants, so results may not apply broadly. There are also unknown risks of using HIV-positive donor hearts in HIV-positive recipients.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.