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HIV drug switch may protect hearts, early study suggests

NCT ID NCT04820933

First seen Nov 01, 2025 · Last updated May 01, 2026 · Updated 31 times

Summary

This early-phase study tested whether switching HIV medications to doravirine (with emtricitabine and tenofovir alafenamide) could reduce heart disease risk in 26 adults with well-controlled HIV and high cholesterol. Researchers measured how the change affected HDL function and other early signs of artery damage. The goal was to see if doravirine is a more heart-friendly option for long-term HIV management.

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Contacts and locations

Locations

  • University of Texas Southwestern

    Dallas, Texas, 75219, United States

  • University of Texas Southwestern Medical Center

    Dallas, Texas, 75219, United States

Conditions

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