Exercise before surgery may slow cancer growth, small study hints
NCT ID NCT04025229
First seen Nov 01, 2025 · Last updated Jun 21, 2026 · Updated 33 times
Summary
This study tested whether a few sessions of high-intensity interval training (HIIT) before surgery could affect cancer cells in women with endometrial cancer. Thirty women with early-stage disease did 4 to 6 exercise sessions before their scheduled hysterectomy. Researchers then compared tissue samples taken before and after exercise to see if the training reduced markers of cancer cell growth.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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UNC Lineberger Comprehensive Cancer Center
Chapel Hill, North Carolina, 27599, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
High intensity interval training (HIIT) exercise
What this could lead to
If it works, this could point toward exercise as a way to slow tumor growth before surgery for endometrial cancer.
What could go wrong
This is a very small, early study with only 30 participants and no comparison group. It measures biological markers, not actual cancer outcomes, so results may not lead to a treatment.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.