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Ancient herbs meet modern dialysis: patch aims to ease pain and depression

NCT ID NCT07380581

Symptom relief Sponsor: Chang Gung Memorial Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested a traditional Chinese medicine patch made from herbs like ginger and Artemisia on 21 dialysis patients who had pain from their fistula. The patch was placed on specific acupoints during dialysis sessions for 4 weeks. Researchers measured pain, depression, and quality of life to see if the patch could help without extra drugs.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
herbal patch (Artemisia princeps, ginger, and Draconis Sanguis extract)
What this could lead to
If it works, this could offer a simple, drug-free way to manage fistula pain and improve mood for people on dialysis.
What could go wrong
This is a very small, early-phase trial (21 people) with no blinding details confirmed, so results may not be reliable or apply to everyone. Herbal patches can sometimes cause skin irritation.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 1/2

Runs two stages together: safety and dose first, then whether the treatment works.

Participants

21 people

The number who actually took part.

Started

Feb 2024

Finished

Aug 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

20 to 80 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * maintenance HD \> 6 months , * reporting fistula pain during HD sessions that was associated with a hypersensitive palpable nodule in a taut band, at least 6 times in the past month, * a NRS pain score \>4, * no changes in pain relievers such as NSAIDs, opioids, topical ointments, or muscle relaxants over the past week, * voluntarily agreed to participate in the trial and presented written informed consent. Exclusion Criteria: * severe comorbid organ dysfunction, * existence of cervical radiculopathy or thoracic outlet syndrome * inflammation of the skin or soft tissue at the fistula site, * dementia, * psychiatric diseases, * allergy to herbal patch * currently participating in other clinical studies

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Conditions

The condition(s) this trial relates to.

chronic renal failure syndrome end stage renal failure Facial Pain myofascial pain syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

End stage chronic renal failure Myofacial pain

Contacts and locations

Locations

  • Chang Gung Memorial Hospital in Kaohsiung branch

    Kaohsiung City, 83301, Taiwan

More trials for these conditions

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