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A shot of numbing relief: could trigger point injections cut opioid use after neck surgery?

NCT ID NCT04640896

Symptom relief Sponsor: George Washington University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 13, 2026 · Last updated Aug 14, 2026 · Updated 1 time

Summary

This trial tests whether giving trigger point injections—small amounts of numbing medication into tender neck muscles—shortly after anterior cervical surgery can reduce pain and the need for opioid painkillers. Patients undergoing elective anterior neck surgery are randomly assigned to receive either the injections or standard pain management. The study measures pain levels and opioid use in the first 24 hours after the procedure.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Trigger point injections with bupivacaine, a numbing medication, given shortly after surgery
What this could lead to
If effective, this approach could offer a way to ease post-surgical neck pain and reduce reliance on opioid painkillers.
What could go wrong
This is a small, early-stage trial, and results may not apply to all patients. There is a risk of injection-related side effects, and the benefit over standard care is not yet proven.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 4

Runs after approval, following long-term safety and how well the treatment works in everyday use.

Participants

60 people

The number who actually took part.

Started

Nov 2020

Finished

Oct 2023

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Elective anterior cervical surgery Exclusion Criteria: * Emergency surgery * Local anesthetic allergy * Long term opioid usage (not including tramadol and codeine) * Intra-operative complication (e.g. unstable cervical spine)

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Conditions

The condition(s) this trial relates to.

Back Pain Facial Pain Klippel-Feil syndrome myofascial pain syndrome Neck Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cervical fusion Myofacial pain Pain, back Pain, neck

Contacts and locations

Locations

  • George Washington University Hospital

    Washington D.C., District of Columbia, 20037, United States

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