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Can tracking hospital care for liver patients reduce repeat admissions?

NCT ID NCT07727070

Knowledge-focused Sponsor: Fadoi Foundation, Italy Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 27, 2026 · Last updated Jul 28, 2026 · Updated 1 time

Summary

This study follows about 400 adults with liver cirrhosis admitted to internal medicine wards across Italy. Researchers will track how doctors manage hepatic encephalopathy—a brain complication of liver disease—during hospitalization and after discharge. The goal is to identify problems in care that may lead to repeat hospital stays and find ways to prevent them.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could identify gaps in care and help reduce hospital readmissions for liver cirrhosis patients with hepatic encephalopathy.
What could go wrong
This is an observational study, so it cannot prove cause and effect. Results may not apply to other countries or healthcare settings.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 400 people

The number the study aims to enrol. It can still change while the study runs.

Started

Dec 2025

Expected to finish

Aug 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Hospitalization in Internal Medicine

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Age ≥18 years 2. Signed informed consent 3. Diagnosis of liver cirrhosis according to recognized clinical, laboratory, and imaging criteria and/or evidence of portal hypertension or liver stiffness ≥ 20 kPa. Exclusion Criteria: * Patient enrolled in other non-observational clinical trials

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Conditions

The condition(s) this trial relates to.

cirrhosis of liver hepatic encephalopathy portal hypertension

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cirrhoses, liver Hepatic encephalopathy Liver stiffness Portal hypertension related to cirrhosis

Contacts and locations

Locations

  • AORN "A. Cardarelli"

    Naples, Italy

  • AOU "Maggiore della Carità"

    Novara, Italy

  • Azienda Ospedaliera "Carlo Poma"

    Mantua, Italy

  • Azienda Ospedaliero Universitaria "Renato Dulbecco"

    Catanzaro, Italy

  • IRCCS Azienda Ospedaliera-Universitaria Policlinico "S. Orsola"

    Bologna, Italy

  • Isola Tiberina Gemelli-Isola Hospital, Rome

    Roma, Italy

  • Ospedale "A. Perrino"

    Brindisi, Italy

  • Ospedale "Buccheri-La Ferla" Fatebenefratelli

    Palermo, Italy

  • Ospedale "Cervesi"

    Cattolica, Italy

  • Ospedale "Girolamo Fracastoro"

    San Bonifacio, Italy

  • Ospedale "Luigi Cazzavillan"

    Arzignano, Italy

  • Ospedale "S. Maria Annunziata"

    Florence, Italy

  • Ospedale "S. Maria della Misericordia"

    Rovigo, Italy

  • Ospedale "Sacro Cuore di Gesù"

    Gallipoli, Italy

  • Ospedale "San Giovanni di Dio"

    Crotone, Italy

  • Ospedale "San Paolo"

    Savona, Italy

  • Ospedale "Sant'Andrea"

    Lamezia Terme, Italy

  • Ospedale "Santa Maria delle Croci"

    Ravenna, Italy

  • Ospedale "Santo Spirito"

    Casale Monferrato, Italy

  • Ospedale "Umberto I°" di Lugo

    Lugo, Italy

  • Ospedale "Umberto I°" di Nocera

    Nocera Inferiore, Italy

  • Ospedale "Umberto I°" di Siracusa

    Syracuse, Italy

  • Ospedale "Vincenzo Monaldi" - AOS dei Colli

    Naples, Italy

  • Ospedale Centrale di Bolzano

    Bolzano, Italy

  • Ospedale Civile "Giuseppe Mazzini"

    Teramo, Italy

  • Ospedale Civile di Legnano

    Legnano, Italy

  • Ospedale Civile di Voghera

    Voghera, Italy

  • Ospedale Di Camerino

    Province of Macerata, Italy

  • Ospedale Fatebenefratelli e Oftalmico

    Milan, Italy

  • Ospedale Maggiore

    Chieri, Italy

  • Ospedale dei Castelli

    Ariccia, Italy

  • Ospedale del Delta

    Ferrara, Italy

  • Ospedale della Misericordia

    Grosseto, Italy

  • Ospedale di Assisi

    Assisi, Italy

  • Ospedale di Circolo di Varese

    Varese, Italy

  • Ospedale di Cremona

    Cremona, Italy

  • Ospedale di Dolo

    Dolo, Italy

  • Ospedali Riuniti Padova Sud

    Monselice, Italy

  • P.O. "SS. Annunziata"

    Sassari, Italy

  • P.O. di Livorno

    Livorno, Italy

  • Presidio Ospedaliero "San Salvatore"

    L’Aquila, Italy

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