Heated tobacco: how do smokers really puff?
NCT ID NCT07175987
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This completed study in the UK observed 212 cigarette smokers to see how they use heated tobacco products. Participants puffed on devices in a lab setting, and a smaller group used the products at home for 5 days. The goal was to measure puffing patterns and daily consumption, not to test health effects.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- heated tobacco products (HTP devices and sticks)
- What this could lead to
- If successful, this study could help regulators and companies understand how smokers actually use heated tobacco products, potentially informing harm reduction strategies.
- What could go wrong
- This is an observational consumer use study, not a clinical trial testing safety or health effects. Results may not reflect long-term use or health outcomes.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
212 people
The number who actually took part.
- Started
-
Sep 2025
- Finished
-
Sep 2025
- Lead sponsor
-
A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
21 to 65 years
- Sex
-
Anyone
- Healthy volunteers
-
Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Be aged 21-65 years (inclusive) * Be self-reported current 'daily users' of at least 5 CPD and have smoked at least 100 cigarettes in their lifetime. ('daily users' defined as have smoked 5 CPD for at least 27 days out of last 30 days) * Agree to participate in the study and to abide by the study restrictions and requirements, including the use of the assigned Study IP, as described in the ICF. * Agree not to allow any other person to use any product provided to them for use during this study. Exclusion Criteria: * Women who self-report they are pregnant or breastfeeding or could become pregnant or start breastfeeding in the next three months from the study start date. * Women who self-report they are not using adequate methods to prevent pregnancy, which they intend to continue throughout the study. a. Examples of acceptable means of birth control are, but not limited to: i. Surgical sterilization (hysterectomy, bilateral tubal litigation/occlusion, bilateral oophorectomy, bilateral salpingectomy); ii. Established use of oral, implantable, injectable, or transdermal methods of contraception associated with inhibition of ovulation; iii. Physical barrier method (e.g., condom, diaphragm/sponge/cervical cap) with spermicide; iv. Non-hormone releasing intrauterine devices (IUD) or hormone-releasing IUDs (e.g., Mirena or Kyleena); v. Vasectomized partner; vi. Abstinence from heterosexual intercourse (as a lifestyle choice, not just for the purpose of study participation; and vii. Post-menopausal and not on hormone replacement Therapy * People who self- report having pacemakers or other embedded electronic medical devices. * People who self-report having heart disease, high blood pressure, diabetes, depression, or asthma. * People who have ever used HTP. * People who self-report currently quitting or planning to quit all nicotine products in the next 3 months. * People who self-report having participated in tobacco product research in the past 3 months. * People who self-report themselves, or someone in their direct family or close friends, as working in one of the following areas: 1. Advertising 2. Journalism 3. Media 4. Insurance 5. Marketing 6. Market Research 7. Manufacturer or retailer of tobacco or vapor products 8. Public Relations 9. Sale of Alcohol
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Channing Hall
Sheffield, United Kingdom
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