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New sickle cell drug passes heart safety check in healthy volunteers

NCT ID NCT07023029

First seen Oct 31, 2025 · Last updated Jun 13, 2026 · Updated 35 times

Summary

This study tested whether a new medicine called etavopivat, being developed for sickle cell disease, affects the heart's electrical activity. Thirty-three healthy adults received different doses of the drug, a placebo, or an approved heart medication. The goal was to check for any heart rhythm changes before moving to larger patient studies.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • PAREXEL Intl - EPCU-Baltimore

    Baltimore, Maryland, 21225, United States

Conditions

The condition(s) this trial relates to.

sickle cell disease thalassemia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.