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2400 healthy volunteers get scanned to spot silent disease early

NCT ID NCT06906042

Knowledge-focused Sponsor: Institut National de la Santé Et de la Recherche Médicale, France Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Sep 18, 2026 · Updated 1 time

Summary

This study will use MRI and ultrasound to create detailed reference images of the heart, liver, and blood vessels in 2,400 healthy adults across France. By linking these images with health data, researchers hope to better understand normal aging versus disease, especially for conditions like heart and liver disease that often have no early symptoms. The goal is to improve early detection and prevention for everyone.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could help doctors better understand what healthy hearts and livers look like, leading to earlier detection of disease.
What could go wrong
This is an observational study, not a treatment trial. It may not directly change medical practice, and results depend on the diversity of the volunteer group.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 2,400 people

The number the study aims to enrol. It can still change while the study runs.

Started

Sep 2025

Expected to finish

Mar 2033

An estimate. End dates often move.

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Study participants are asymptomatic volunteers from the Constances cohort, whose risk factor profiles are representative of the population in the Île-de-France region (Paris area). Participants are divided into 6 decades from 20 to 80 years with equal distribution of men/women (200 men and 200 women per decade)

Ages

20 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Participation to the Constances cohort * Age ≥ 20 years * No overt cardiovascular or hepatic disease or related symptoms * No known family or personal genetic disease * Affiliation with a social security scheme or beneficiary of such a scheme. * Agreement to sign the consent Exclusion Criteria: * Renal function impairment with GFR \< 60 mL/min/1.73m2 * Deprived of liberty or persons subject to a legal protection measure (under guardianship or trusteeship) * People with contraindications to MRI (claustrophobia, presence of metallic elements…) * Pregnant or breastfeeding woman (pregnancy urinary test before inclusion for women of childbearing age).

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Healthy volunteers Imaging evaluation

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Hôpital Pitié-Salpêtrière

    RECRUITING

    Paris, France

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