Spinal tap may offer headache relief for brain bleed survivors
NCT ID NCT03754335
First seen May 30, 2026 · Last updated Jun 22, 2026 · Updated 4 times
Summary
This study tested whether draining some fluid from the spine (a lumbar puncture) can help relieve severe headaches that often follow a brain aneurysm rupture. The trial involved 74 patients with mild to moderate brain bleeds. Half received a real lumbar puncture, and half received a sham procedure, with both groups also getting standard pain medication. The goal was to see if the fluid removal reduced headache intensity more than the sham procedure.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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University Hospital Toulouse
Toulouse, 31059, France
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
lumbar puncture (spinal tap)
What this could lead to
If it works, this could provide a simple, safe way to reduce severe headaches after a brain aneurysm bleed, improving patient comfort.
What could go wrong
This is a small, completed trial with only 74 participants. The procedure may not significantly reduce pain compared to standard care, and there are risks like infection or bleeding from the lumbar puncture.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.