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Steroids for COVID-19: hidden hepatitis b danger revealed?

NCT ID NCT07154212

Knowledge-focused Sponsor: University Medical Centre Ljubljana Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This completed study looked at whether COVID-19 patients treated with steroids might have a reactivation of hepatitis B virus (HBV). Researchers followed 1,793 hospitalized adults who needed oxygen and received steroids for COVID-19 pneumonia. The goal was to see how well doctors followed HBV screening guidelines and how often the virus reactivated in patients who had past HBV infection.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

1,793 people

The number who actually took part.

Started

Nov 2020

Finished

Apr 2022

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

patients hospitalized and treated with corticosteroids for covid-19

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * hospitalized adult patients with a positive severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ribonucleic acid (RNA) polymerase chain reaction (PCR) test * supplemental oxygen * treated with corticosteroids for COVID-19 pneumonia Exclusion Criteria: * age under 18 years * hospitalized for medical conditions unrelated to COVID-19 * received corticosteroid therapy for non-COVID-19 reasons

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Conditions

The condition(s) this trial relates to.

COVID-19 hepatitis B virus infection Hypoxia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

COVID-19 pneumonia Hepatitis B Hypoxemia

Contacts and locations

Locations

  • University Medical Centre Ljubljana

    Ljubljana, Slovenia

More trials for these conditions

Other studies related to the condition(s) this trial covers.