Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

Gut bacteria linked to brain changes in Alzheimer's, Parkinson's, and MS

NCT ID NCT05934188

Knowledge-focused Sponsor: IRCCS San Camillo, Venezia, Italy Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This observational study looks at how gut bacteria relate to brain structure and function in healthy aging and in people with early Alzheimer's, Parkinson's, or multiple sclerosis. Researchers will use brain scans, stool samples, blood tests, and cognitive assessments in 200 participants. The goal is to find early markers that could help detect or understand these diseases better.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this study could identify early markers for neurodegenerative diseases, potentially leading to new ways to detect or monitor these conditions.
What could go wrong
This is an observational study, not a treatment trial. It may find correlations but cannot prove cause and effect. Results may not lead to immediate clinical applications.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 200 people

The number the study aims to enrol. It can still change while the study runs.

Started

May 2023

Expected to finish

Apr 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The groups will be selected from local community sample, hospital and general practitioners (gp).

Ages

20 to 90 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

INCLUSION CRITERIA: Healthy Young and Old Subjects: * 20-50 or 60-90 years old * Cognitively healthy (Mini-Mental State examination ≥ 26) * Absence of significant neurological disorders Patients with prodromal Alzheimer's Disease: * Subjective cognitive complaint (corroborated by the informant) * Episodic memory deficit on neuropsychological testing * Clinical Dementia Rating = 0.5 * Mini-Mental State Examination (MMSE) \> 23 * Independently functioning in activities of daily living Patients with Parkinson's Disease: * Recent diagnosis of Parkinson's Disease * Mild-moderate score at the Unified Parkinson's Disease Rating Scale (UPDRS) * Cognitively healthy (Mini-Mental State examination ≥ 26) * In case of taking medications for Parkinson's Disease: stable dosage for at least 6 months Patients with Multiple Sclerosis: * Recent diagnosis of relapsing-remitting Multiple Sclerosis * Expanded Disability Status Scale score ≤ 4.0 * Cognitively healthy (Mini-Mental State examination ≥ 26) * In case of taking medications for Multiple Sclerosis: stable dosage for at least 6 months. EXCLUSION CRITERIA: For both healthy participants and patients: * Contraindications to magnetic resonance imaging (metal implant in body, known claustrophobia, pacemakers) * Severe comorbidities * Antibiotics treatments over the last 3 months

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Healthy are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

Alzheimer disease multiple sclerosis Parkinson disease relapsing-remitting multiple sclerosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Healthy Multiple sclerosis Parkinson disease Prodromal Alzheimer's disease

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    3 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli

    RECRUITING

    Brescia, 25125, Italy

  • IRCCS San Camillo

    RECRUITING

    Venice-Lido, Venice, 30126, Italy

  • Università Ca' Foscari Venezia

    RECRUITING

    Venice, 30123, Italy

More trials for these conditions

Other studies related to the condition(s) this trial covers.