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Tiny blood vessel coating may hold key to better surgery monitoring

NCT ID NCT06285526

Knowledge-focused Sponsor: University Hospital, Rouen Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at a thin layer inside blood vessels called the glycocalyx in 78 adults having major abdominal surgery. Researchers used a special camera to measure changes in this layer during and after surgery. The goal was to see if tracking glycocalyx thickness could help doctors better manage anesthesia and fluids, but the study did not test any treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

78 people

The number who actually took part.

Started

Jul 2022

Finished

May 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patient undergoing major abdominal surgery by cytoreduction combined with an intraperitoneal chemotherapy bath (HIPEC) or cephalic duodeno-pancreatectomy (CDP) with epidural analgesia planned in accordance with the department's usual practice

Ages

18 to 75 years

Sex

Anyone

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: For the HIPEC group : * Adult patients * Age \< 75 years * Receiving HIPEC for primary or secondary peritoneal carcinosis For the CDP group : * Adult patient * Age \< 75 years * Receiving CDP for pancreatic neoplasia * Patient who has read and understood the information letter and does not object to taking part in the study * Patient affiliated to a social security scheme Exclusion Criteria: * Secondary distant peritoneal metastases * Chronic heart failure * Chronic liver failure at stage C of the Child-Pugh score * Stage IV or V chronic renal failure * Inflammation of the sublingual buccal mucosa or injury that may locally influence sublingual microcirculation * Patient refusal * Person deprived of liberty by an administrative or judicial decision or person placed under court protection or guardianship

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Conditions

The condition(s) this trial relates to.

pancreatic neoplasm peritoneal carcinomatosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Major abdominal surgery

Contacts and locations

Locations

  • Rouen University Hospital

    Rouen, 76000, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.