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Tiny lung puffs during surgery could speed recovery

NCT ID NCT07239557

Knowledge-focused Sponsor: Sixth Affiliated Hospital, Sun Yat-sen University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only This study
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests how often doctors should give a brief lung inflation (called a recruitment maneuver) during abdominal laparoscopic surgery to keep the lungs open. Fifty-two older adults having elective surgery will receive these puffs at different intervals, starting every 30 minutes. The goal is to find the timing that works for 90% of patients, reducing lung collapse and complications after surgery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could establish a standard breathing technique during surgery to reduce lung collapse and speed up recovery after abdominal operations.
What could go wrong
This is a small, early-stage trial with only 52 participants, so results may not apply to all patients. The procedure itself carries minor risks like temporary changes in blood pressure or oxygen levels.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 52 people

The number the study aims to enrol. It can still change while the study runs.

Started

Dec 2025

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

65 to 80 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age 65-80 years * Undergoing elective laparoscopic anterior resection (expected mechanical ventilation duration 2-5 hours) * Intermediate risk for postoperative pulmonary complications * Room air SpO₂ ≥94% Exclusion Criteria: * History of pneumonia within 1 month or mechanical ventilation ≥1 hour * Preoperative 12-zone LUS with any single zone score ≥2 * Preoperative shunt fraction ≥10% * Progressive neuromuscular disease * Severe emphysema/COPD or subpleural bullae ≥2 cm * Intracranial hypertension * Participation in other studies or refusal to participate

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Conditions

The condition(s) this trial relates to.

middle lobe syndrome Pulmonary Atelectasis Respiratory Aspiration

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Atelectasis Lung ultrasound score Lung-protective ventilation Major abdominal surgery Postoperative pulmonary complications

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    The full official record for this study. This one lists no contact details, but it is the first place any would appear.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • SixthSunYetSen

    Guangzhou, Guangdong, 510600, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.