Scientists test new way to track nutrient use in bone marrow cells
NCT ID NCT03384108
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This pilot study aims to see if a new method can measure how healthy bone marrow plasma cells use glutamine, an important nutrient. Twenty healthy adults will receive an intravenous infusion of a special labeled glutamine, followed by a bone marrow aspiration. The goal is to compare this in-person approach with lab-based methods, laying groundwork for future disease research.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- 5-13C-Glutamine (a labeled form of glutamine given intravenously)
- What this could lead to
- If successful, this method could help researchers understand how plasma cells use nutrients, potentially guiding future treatments for diseases like multiple myeloma.
- What could go wrong
- This is a very early, small pilot study in healthy people, not patients. It only tests the measurement method, not a treatment, so it may not lead directly to any therapy.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 20 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Sep 2017
- Expected to finish
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Jan 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 60 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Ages 18-60 * Able to provide written consent Exclusion Criteria: * Renal Failure * Pregnancy * Active steroid use * Active liver Disease * Anemia (Hemoglobin \< 12.5 g/dL in men and \< 11.5 g/dL in women) * H/O alcohol use (average \> 2 drinks per day) * BMI \> 30
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Mayo Clinic
RECRUITINGRochester, Minnesota, 55905, United States
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