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Can One-Piece tumour removal improve bladder cancer outcomes?

NCT ID NCT04934540

Knowledge-focused Sponsor: Chinese University of Hong Kong Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 03, 2026 · Last updated Aug 04, 2026 · Updated 1 time

Summary

This global registry is collecting data on a surgical technique called en bloc resection of bladder tumour (ERBT), which removes the tumour in one piece rather than in fragments. The goal is to see whether this approach leads to complete tumour removal and better recurrence-free survival in bladder cancer patients. Over a 5-year period, researchers will track outcomes in about 2,000 adults undergoing ERBT. The findings could help clarify the role of this technique in managing bladder cancer.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
En bloc resection of bladder tumour (ERBT), a surgical technique that removes the tumour in one piece
What this could lead to
If successful, this registry could clarify whether ERBT improves complete tumour removal and reduces recurrence in bladder cancer, potentially guiding future surgical standards.
What could go wrong
As a registry, it only observes outcomes without a control group, so it cannot prove ERBT is better than standard surgery. Results may also vary across global sites.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 2,000 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jan 2020

Expected to finish

Dec 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients who are diagnosed with bladder tumors upon flexible cystoscopy and planning for ERBT

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adult patients \>=18 years old with informed consent * Presence of bladder tumour undergoing transurethral ERBT Exclusion Criteria: * Presence or previous history of upper tract urothelial carcinoma * Presence of other active malignancy * Pregnancy

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Conditions

The condition(s) this trial relates to.

urinary bladder carcinoma Urinary Bladder Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Bladder cancer

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    2 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • North District Hospital

    RECRUITING

    Hong Kong, Hong Kong

  • Prince of Wales Hospital

    RECRUITING

    Hong Kong, Hong Kong

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