One-Stop stroke care could save minutes and lives
NCT ID NCT07052045
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This trial tests whether doing brain scans and clot-removal procedures in the same room speeds up treatment for severe strokes. About 390 patients with suspected large-vessel blockages will be randomly assigned to either the usual two-room process or a one-room approach. The goal is to see if faster treatment leads to less disability at 90 days.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- One-Stop management (flat panel CT imaging and endovascular therapy in the same room)
- What this could lead to
- If successful, this approach could cut treatment delays, helping more stroke patients recover independence and reducing long-term disability.
- What could go wrong
- This is a mid-sized trial testing a workflow change, not a new drug. The imaging method may be slightly less accurate for some stroke types, and results may not apply to all hospitals.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 390 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Dec 2025
- Expected to finish
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Nov 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Symptoms suggestive of an acute ischemic stroke caused by a large or medium vessel occlusion as defined by a National Institute of Health Stroke Scale (NIHSS) Score of ≥ 10 points * Patient presents directly to the treating hospital (mothership patient) within 4.5 hours of last seen well (LSW) * Age ≥ 18 years * Patient was independent in daily activities prior to the stroke (pre stroke modified Rankin Scale of 0 - 2) * Endovascular treatment team available (Neurologist, Interventionist, Anesthesiologist, Nursery, Technicians) * Informed Consent as documented by signature or fulfilling the criteria for emergency consent procedures Exclusion Criteria: * Severe comorbidities, which will likely prevent improvement or follow-up * In-hospital stroke * Clinical symptoms suggestive of intracranial hemorrhage (deterioration of patient during transport, vomiting or depressed consciousness) * Strong suspicion of functional neurological symptom disorder / conversion disorder * Hemodynamically unstable patients who require advanced vital support * Angiography room occupied by other procedure
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
2 sites in 2 countries. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Klinik für Neurologie, Universitätsklinik der Paracelsus
RECRUITINGNuremberg, 90471, Germany
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University Hospital Basel
NOT_YET_RECRUITINGBasel, 4031, Switzerland
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Other studies related to the condition(s) this trial covers.
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