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Garlic supplement shows promise for dialysis patients

NCT ID NCT07461012

Disease control Sponsor: Ain Shams University Source: ClinicalTrials.gov ↗

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether garlic supplements can improve blood vessel function and reduce inflammation in adults with kidney failure who are on hemodialysis. Fifty-eight patients took garlic extract or a placebo for a period of time. Researchers measured markers of inflammation and blood vessel health to see if garlic could lower the risk of heart problems, a common complication in dialysis patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

58 people

The number who actually took part.

Started

Oct 2025

Finished

Dec 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adult patients aged above 18 years with confirmed diagnosis of CKD. * Patients on HD for at least 3 months before enrollment. * Patients not participating in other clinical trials. * Physically stable. Exclusion Criteria: * Patients diagnosed with digestive diseases as ileal bypass. * Patients with a history of hemorrhagic disorders or taking medications like warfarin. * Patients sensitive to garlic. * Patients with history of alcohol or drug abuse. * Patients receiving other anti-inflammatory medications (e.g. use of vitamin E at a dose higher than 60 IU per day or vitamin C higher than 500 mg per day)

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Conditions

The condition(s) this trial relates to.

chronic kidney disease end stage renal failure Inflammation inflammatory disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CKD Endothelial dysfunction Hemodialysis Inflammation

Contacts and locations

Locations

  • faculty of pharmacy Ain Shams university

    Cairo, Egypt

More trials for these conditions

Other studies related to the condition(s) this trial covers.