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New hope for rare bone cancer: targeted drug added to chemo in major trial

NCT ID NCT02306161

Disease control Sponsor: National Cancer Institute (NCI) Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jul 30, 2026 · Updated 3 times

Summary

This study tests whether adding a targeted drug called ganitumab to standard chemotherapy helps people with newly diagnosed Ewing sarcoma that has spread. The trial includes 312 participants and aims to see if the combination improves survival without the cancer growing back. The approach is not a cure, but aims to better control the disease.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 3

Large-scale testing in a bigger group. Usually the last step before a treatment can be approved.

Participants

312 people

The number who actually took part.

Started

Dec 2014

Expected to finish

Sep 2026

An estimate. End dates often move.

Lead sponsor

A government research agency

The lead sponsor is the US National Institutes of Health.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

Up to 50 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients with histologic diagnosis (by institutional pathologist) of newly diagnosed Ewing sarcoma or peripheral primitive neuroectodermal tumor (PNET) arising from bone or soft tissue and with metastatic disease involving lung, bone, bone marrow, or other metastatic site * For the purpose of this study metastatic disease is defined as one or more of the following: * Lesions which are discontinuous from the primary tumor, are not regional lymph nodes, and do not share a bone or body cavity with the primary tumor; skip lesions in the same bone as the primary tumor do not constitute metastatic disease; skip lesions in an adjacent bone are considered bone metastases; if there is any doubt whether lesions are metastatic, a biopsy of those lesions should be performed * Contralateral pleural effusion and/or contralateral pleural nodules * Distant lymph node involvement * Patients with pulmonary nodules are considered to have metastatic disease if the patient has: * Solitary nodule \>= 0.5 cm or multiple nodules of \>= 0.3 cm unless lesion is biopsied and negative for tumor * Patients with solitary nodule \< 0.5 cm or multiple nodules \< 0.3 cm are not considered to have lung metastasis unless biopsy documents tumor * Bone marrow metastatic disease is based on morphologic evidence of Ewing sarcoma based on hematoxylin and eosin (H\&E) stains; in the absence of morphologic evidence of marrow involvement on H\&E, patients with bone marrow involvement detected ONLY by flow cytometry, reverse-transcriptase (RT)-polymerase chain reaction (PCR), fluorescence in situ hybridization (FISH), or immunohistochemistry will NOT be considered to have clinical bone marrow involvement for the purposes of this study * This study requires bilateral bone marrow biopsies at study entry; the suggested approach for patients with large pelvic tumors in which a posterior iliac crest bone marrow biopsy would track through the tumor is to instead undergo 2 marrow biopsies on the contralateral side (either 2 posterior biopsies or one posterior and one anterior biopsy) * Bone metastasis: This study utilizes whole body FDG-PET scans to screen patients for bone metastases; areas suspicious for bone metastasis based on FDG-PET scans require confirmatory anatomic imaging with either MRI or computed tomography (CT) (whole body FDG-PET/CT or FDG-PET/magnetic resonance \[MR\] scan acceptable); whole body technetium bone scans may be performed at the discretion of the investigator and are not required; for patients without other sites of metastatic disease whose sole metastatic site to qualify for study entry is a single area suspicious for bone metastasis identified by FDG-PET, confirmatory biopsy or anatomic imaging evidence of an associated soft tissue mass at that site is required for study entry * Patients must have adequate tumor tissue to meet the minimum requirement for submission * Enrolling institutions are reminded that submission of pre-treatment serum, tumor tissue and whole blood is required * Patients should only have had a biopsy of the primary tumor without an attempt at complete or partial resection; patients will still be eligible if excision was attempted or accomplished as long as adequate anatomic imaging (MRI for most primary tumor sites) was obtained prior to surgery * Creatinine clearance or radioisotope glomerular filtration rate (GFR) \>= 70 mL/min/1.73 m\^2 or a serum creatinine based on age/gender as follows (performed within 7 days prior to enrollment): * Age \< 6 months: Maximum serum creatinine (mg/dL): 0.4 for males and females * Age 6 months to \< 1 year: Maximum serum creatinine (mg/dL): 0.5 for males and females * Age 1 to \< 2 years: Maximum serum creatinine (mg/dL): 0.6 for males and females * Age 2 to \< 6 years: Maximum serum creatinine (mg/dL): 0.8 for males and females * Age 6 to \< 10 years: Maximum serum creatinine (mg/dL): 1 for males and females * Age 10 to \< 13 years: Maximum serum creatinine (mg/dL): 1.2 for males and females * Age 13 to \< 16 years: Maximum serum creatinine (mg/dL): 1.5 for males and 1.4 for females * Age \>= 16 years: Maximum serum creatinine (mg/dL): 1.7 for males and 1.4 for females * Total bilirubin =\< 1.5 x upper limit of normal (ULN) for age (performed within 7 days prior to enrollment), and * Serum glutamate pyruvate transaminase (SGPT) (alanine aminotransferase \[ALT\]) \< 3 x upper limit of normal (ULN) for age (performed within 7 days prior to enrollment) (except for patients with liver metastasis who may enroll if ALT \< 5 times ULN for age) * Shortening fraction of \>= 27% or * Ejection fraction of \>= 50% * Patients must have a normal blood sugar level for age to participate; if an initial random draw (ie. non-fasting) blood glucose value is out of range, it is acceptable to repeat this test as a fasting draw * All patients and/or their parents or legal guardians must sign a written informed consent * All institutional, Food and Drug Administration (FDA), and National Cancer Institute (NCI) requirements for human studies must be met Exclusion Criteria: * Patients with regional node involvement as their only site of disease beyond the primary tumor will not be eligible * Patients whose primary tumors arise in the intra-dural soft tissue (e.g. brain and spinal cord) are not eligible * Patients who have received prior chemotherapy or radiation therapy are not eligible * Female patients of childbearing potential are not eligible unless a negative pregnancy test result has been obtained; lactating females are not eligible unless they have agreed not to breastfeed their infants for the duration of protocol therapy; sexually active patients of reproductive potential are not eligible unless they have agreed to use an effective contraceptive method for the duration of protocol therapy * Patients with known pre-existing diabetes mellitus will be excluded from study * Patients receiving chronic pharmacologic doses of corticosteroids are not eligible; for the purposes of eligibility, chronic exposure is defined as anticipated exposure of \> 3 weeks, including the sum of both pre-enrollment and anticipated post-enrollment dosing; patients on acute corticosteroid therapy (=\< 3 weeks of total planned exposure) must still meet the normal blood glucose requirement; patients receiving chronic inhaled corticosteroids or chronic physiologic replacement doses of corticosteroids are eligible

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Conditions

The condition(s) this trial relates to.

bone marrow cancer Ewing sarcoma metastatic carcinoma in the bone metastatic malignant neoplasm peripheral primitive neuroectodermal tumor peripheral primitive neuroectodermal tumor of bone peripheral primitive neuroectodermal tumor of soft tissues

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Metastatic Ewing sarcoma Metastatic malignant neoplasm in the bone Metastatic malignant neoplasm in the bone marrow Metastatic malignant neoplasm in the lung Metastatic peripheral primitive neuroectodermal tumor of bone Peripheral primitive neuroectodermal tumor of soft tissues

Contacts and locations

Locations

  • AdventHealth Littleton

    Littleton, Colorado, 80122, United States

  • AdventHealth Orlando

    Orlando, Florida, 32803, United States

  • AdventHealth Parker

    Parker, Colorado, 80138, United States

  • AdventHealth Porter

    Denver, Colorado, 80210, United States

  • Advocate Children's Hospital-Oak Lawn

    Oak Lawn, Illinois, 60453, United States

  • Advocate Children's Hospital-Park Ridge

    Park Ridge, Illinois, 60068, United States

  • Albany Medical Center

    Albany, New York, 12208, United States

  • Alberta Children's Hospital

    Calgary, Alberta, T3B 6A8, Canada

  • Alegent Health Bergan Mercy Medical Center

    Omaha, Nebraska, 68124, United States

  • Alegent Health Immanuel Medical Center

    Omaha, Nebraska, 68122, United States

  • Alegent Health Lakeside Hospital

    Omaha, Nebraska, 68130, United States

  • Alegent Health Mercy Hospital

    Council Bluffs, Iowa, 51503, United States

  • Alfred I duPont Hospital for Children

    Wilmington, Delaware, 19803, United States

  • Alliance for Childhood Diseases/Cure 4 the Kids Foundation

    Las Vegas, Nevada, 89135, United States

  • Ann M Wierman MD LTD

    Las Vegas, Nevada, 89128, United States

  • Arkansas Children's Hospital

    Little Rock, Arkansas, 72202-3591, United States

  • Arnold Palmer Hospital for Children

    Orlando, Florida, 32806, United States

  • Ascension Saint Vincent Indianapolis Hospital

    Indianapolis, Indiana, 46260, United States

  • Augusta University Medical Center

    Augusta, Georgia, 30912, United States

  • BI-LO Charities Children's Cancer Center

    Greenville, South Carolina, 29605, United States

  • Banner Children's at Desert

    Mesa, Arizona, 85202, United States

  • Banner University Medical Center - Tucson

    Tucson, Arizona, 85719, United States

  • Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center

    Houston, Texas, 77030, United States

  • Baystate Medical Center

    Springfield, Massachusetts, 01199, United States

  • Beacon Kalamazoo

    Kalamazoo, Michigan, 49048, United States

  • Bethesda North Hospital

    Cincinnati, Ohio, 45242, United States

  • Blank Children's Hospital

    Des Moines, Iowa, 50309, United States

  • British Columbia Children's Hospital

    Vancouver, British Columbia, V6H 3V4, Canada

  • Bronson Battle Creek

    Battle Creek, Michigan, 49017, United States

  • Bronson Methodist Hospital

    Kalamazoo, Michigan, 49007, United States

  • C S Mott Children's Hospital

    Ann Arbor, Michigan, 48109, United States

  • CHI Health Good Samaritan

    Kearney, Nebraska, 68847, United States

  • CHI Saint Vincent Cancer Center Hot Springs

    Hot Springs, Arkansas, 71913, United States

  • CHU de Quebec-Centre Hospitalier de l'Universite Laval (CHUL)

    Québec, G1V 4G2, Canada

  • CancerCare Manitoba

    Winnipeg, Manitoba, R3E 0V9, Canada

  • Cardinal Glennon Children's Medical Center

    St Louis, Missouri, 63104, United States

  • Carilion Children's

    Roanoke, Virginia, 24014, United States

  • Carle Cancer Center

    Urbana, Illinois, 61801, United States

  • Carle Physician Group-Effingham

    Effingham, Illinois, 62401, United States

  • Carle Physician Group-Mattoon/Charleston

    Mattoon, Illinois, 61938, United States

  • Carle at The Riverfront

    Danville, Illinois, 61832, United States

  • Carolinas Medical Center/Levine Cancer Institute

    Charlotte, North Carolina, 28203, United States

  • Carson Tahoe Regional Medical Center

    Carson City, Nevada, 89703, United States

  • Central Care Cancer Center - Bolivar

    Bolivar, Missouri, 65613, United States

  • Central Vermont Medical Center/National Life Cancer Treatment

    Berlin Corners, Vermont, 05602, United States

  • Centre Hospitalier Universitaire Sainte-Justine

    Montreal, Quebec, H3T 1C5, Canada

  • Chancellor Center for Oncology

    Newburgh, Indiana, 47630, United States

  • Children's Healthcare of Atlanta - Arthur M Blank Hospital

    Atlanta, Georgia, 30329, United States

  • Children's Hospital

    London, Ontario, N6A 5W9, Canada

  • Children's Hospital Colorado

    Aurora, Colorado, 80045, United States

  • Children's Hospital Los Angeles

    Los Angeles, California, 90027, United States

  • Children's Hospital Medical Center of Akron

    Akron, Ohio, 44308, United States

  • Children's Hospital New Orleans

    New Orleans, Louisiana, 70118, United States

  • Children's Hospital and Medical Center of Omaha

    Omaha, Nebraska, 68114, United States

  • Children's Hospital at Montefiore

    The Bronx, New York, 10467, United States

  • Children's Hospital of Alabama

    Birmingham, Alabama, 35233, United States

  • Children's Hospital of Eastern Ontario

    Ottawa, Ontario, K1H 8L1, Canada

  • Children's Hospital of Orange County

    Orange, California, 92868, United States

  • Children's Hospital of Philadelphia

    Philadelphia, Pennsylvania, 19104, United States

  • Children's Hospital of Pittsburgh of UPMC

    Pittsburgh, Pennsylvania, 15224, United States

  • Children's Hospital of San Antonio

    San Antonio, Texas, 78207, United States

  • Children's Hospital of The King's Daughters

    Norfolk, Virginia, 23507, United States

  • Children's Hospital of Wisconsin

    Milwaukee, Wisconsin, 53226, United States

  • Children's Hospitals and Clinics of Minnesota - Minneapolis

    Minneapolis, Minnesota, 55404, United States

  • Children's Mercy Hospitals and Clinics

    Kansas City, Missouri, 64108, United States

  • Children's National Medical Center

    Washington D.C., District of Columbia, 20010, United States

  • Cincinnati Children's Hospital Medical Center

    Cincinnati, Ohio, 45229, United States

  • City of Hope Comprehensive Cancer Center

    Duarte, California, 91010, United States

  • Cleveland Clinic Foundation

    Cleveland, Ohio, 44195, United States

  • CommonSpirit Cancer Center Mercy

    Durango, Colorado, 81301, United States

  • CommonSpirit Saint Anthony Hospital Cancer Center

    Lakewood, Colorado, 80228, United States

  • CommonSpirit Saint Joseph Hospital - Bardstown

    Bardstown, Kentucky, 40004, United States

  • CommonSpirit Saint Joseph Hospital London

    London, Kentucky, 40741, United States

  • CommonSpirit Saint Joseph Medical Center - East Lexington

    Lexington, Kentucky, 40509, United States

  • Commonwealth Cancer Center-Corbin

    Corbin, Kentucky, 40701, United States

  • Comprehensive Cancer Centers of Nevada-Horizon Ridge

    Henderson, Nevada, 89052, United States

  • Connecticut Children's Medical Center

    Hartford, Connecticut, 06106, United States

  • Cook Children's Medical Center

    Fort Worth, Texas, 76104, United States

  • Corewell Health Children's

    Royal Oak, Michigan, 48073, United States

  • Corewell Health Grand Rapids Hospitals - Butterworth Hospital

    Grand Rapids, Michigan, 49503, United States

  • Corewell Health Grand Rapids Hospitals - Helen DeVos Children's Hospital

    Grand Rapids, Michigan, 49503, United States

  • Corewell Health Lakeland Hospitals - Marie Yeager Cancer Center

    Saint Joseph, Michigan, 49085, United States

  • Corewell Health Lakeland Hospitals - Niles Hospital

    Niles, Michigan, 49120, United States

  • Corewell Health Lakeland Hospitals - Saint Joseph Hospital

    Saint Joseph, Michigan, 49085, United States

  • Corewell Health Reed City Hospital

    Reed City, Michigan, 49677, United States

  • Covenant Children's Hospital

    Lubbock, Texas, 79410, United States

  • Cox Cancer Center Branson

    Branson, Missouri, 65616, United States

  • CoxHealth South Hospital

    Springfield, Missouri, 65807, United States

  • Dana-Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

  • Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center

    Lebanon, New Hampshire, 03756, United States

  • Dayton Children's Hospital

    Dayton, Ohio, 45404, United States

  • Deaconess Clinic Downtown

    Evansville, Indiana, 47713, United States

  • Dell Children's Medical Center of Central Texas

    Austin, Texas, 78723, United States

  • Drexel University School of Medicine

    Philadelphia, Pennsylvania, 19102, United States

  • Driscoll Children's Hospital

    Corpus Christi, Texas, 78411, United States

  • Duke University Medical Center

    Durham, North Carolina, 27710, United States

  • East Tennessee Childrens Hospital

    Knoxville, Tennessee, 37916, United States

  • Eastern Maine Medical Center

    Bangor, Maine, 04401, United States

  • El Paso Children's Hospital

    El Paso, Texas, 79905, United States

  • Essentia Health Cancer Center

    Duluth, Minnesota, 55805, United States

  • Franciscan Research Center-Northwest Medical Plaza

    Tacoma, Washington, 98405, United States

  • Franciscan Saint Anthony Health-Michigan City

    Michigan City, Indiana, 46360, United States

  • Fred and Pamela Buffett Cancer Center - Kearney

    Kearney, Nebraska, 68845, United States

  • Freeman Health System

    Joplin, Missouri, 64804, United States

  • Geisinger Medical Center

    Danville, Pennsylvania, 17822, United States

  • Glens Falls Hospital

    Glens Falls, New York, 12801, United States

  • Golisano Children's Hospital of Southwest Florida

    Fort Myers, Florida, 33908, United States

  • Good Samaritan Hospital - Cincinnati

    Cincinnati, Ohio, 45220, United States

  • Greater Regional Medical Center

    Creston, Iowa, 50801, United States

  • Hackensack University Medical Center

    Hackensack, New Jersey, 07601, United States

  • Harrison HealthPartners Hematology and Oncology-Poulsbo

    Poulsbo, Washington, 98370, United States

  • Heartland Regional Medical Center

    Saint Joseph, Missouri, 64506, United States

  • Hematology and Oncology Consultants PC

    Omaha, Nebraska, 68122, United States

  • Henry Ford Health Saint John Hospital

    Detroit, Michigan, 48236, United States

  • Highline Medical Center-Main Campus

    Burien, Washington, 98166, United States

  • Hope Cancer Care of Nevada-Pahrump

    Pahrump, Nevada, 89048, United States

  • Hospital for Sick Children

    Toronto, Ontario, M5G 1X8, Canada

  • Hurley Medical Center

    Flint, Michigan, 48503, United States

  • Huron Medical Center PC

    Port Huron, Michigan, 48060, United States

  • IWK Health Centre

    Halifax, Nova Scotia, B3K 6R8, Canada

  • Inova Fairfax Hospital

    Falls Church, Virginia, 22042, United States

  • Janeway Child Health Centre

    St. John's, Newfoundland and Labrador, A1B 3V6, Canada

  • Jewish Hospital

    Louisville, Kentucky, 40202, United States

  • Jewish Hospital Medical Center South

    Shepherdsville, Kentucky, 40165, United States

  • Johns Hopkins All Children's Hospital

    St. Petersburg, Florida, 33701, United States

  • Johns Hopkins University/Sidney Kimmel Cancer Center

    Baltimore, Maryland, 21287, United States

  • Kaiser Permanente Downey Medical Center

    Downey, California, 90242, United States

  • Kaiser Permanente Moanalua Medical Center

    Honolulu, Hawaii, 96819, United States

  • Kaiser Permanente-Oakland

    Oakland, California, 94611, United States

  • Kapiolani Medical Center for Women and Children

    Honolulu, Hawaii, 96826, United States

  • Kingston Health Sciences Centre

    Kingston, Ontario, K7L 2V7, Canada

  • Lake Huron Medical Center

    Port Huron, Michigan, 48060, United States

  • Laura and Isaac Perlmutter Cancer Center at NYU Langone

    New York, New York, 10016, United States

  • Legacy Emanuel Children's Hospital

    Portland, Oregon, 97227, United States

  • Lehigh Valley Hospital - Muhlenberg

    Bethlehem, Pennsylvania, 18017, United States

  • Lehigh Valley Hospital-Cedar Crest

    Allentown, Pennsylvania, 18103, United States

  • Loma Linda University Medical Center

    Loma Linda, California, 92354, United States

  • Longmont United Hospital

    Longmont, Colorado, 80501, United States

  • Loyola University Medical Center

    Maywood, Illinois, 60153, United States

  • Lucile Packard Children's Hospital Stanford University

    Palo Alto, California, 94304, United States

  • Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center

    Torrance, California, 90502, United States

  • Lurie Children's Hospital-Chicago

    Chicago, Illinois, 60611, United States

  • Madigan Army Medical Center

    Tacoma, Washington, 98431, United States

  • Maine Children's Cancer Program

    Scarborough, Maine, 04074, United States

  • Marshfield Medical Center-Marshfield

    Marshfield, Wisconsin, 54449, United States

  • Mary Bridge Children's Hospital and Health Center

    Tacoma, Washington, 98405, United States

  • Massachusetts General Hospital Cancer Center

    Boston, Massachusetts, 02114, United States

  • Mayo Clinic in Rochester

    Rochester, Minnesota, 55905, United States

  • McMaster Children's Hospital at Hamilton Health Sciences

    Hamilton, Ontario, L8N 3Z5, Canada

  • MedStar Georgetown University Hospital

    Washington D.C., District of Columbia, 20007, United States

  • Medical City Dallas Hospital

    Dallas, Texas, 75230, United States

  • Medical University of South Carolina

    Charleston, South Carolina, 29425, United States

  • Memorial GYN Plus

    Ooltewah, Tennessee, 37363, United States

  • Memorial Health University Medical Center

    Savannah, Georgia, 31404, United States

  • Memorial Hospital

    Chattanooga, Tennessee, 37404, United States

  • Memorial Regional Hospital/Joe DiMaggio Children's Hospital

    Hollywood, Florida, 33021, United States

  • Mercy Cancer Center-West Lakes

    Clive, Iowa, 50325, United States

  • Mercy Clinic-Rolla-Cancer and Hematology

    Rolla, Missouri, 65401, United States

  • Mercy Hospital Joplin

    Joplin, Missouri, 64804, United States

  • Mercy Hospital Oklahoma City

    Oklahoma City, Oklahoma, 73120, United States

  • Mercy Hospital Saint Louis

    St Louis, Missouri, 63141, United States

  • Mercy Hospital Springfield

    Springfield, Missouri, 65804, United States

  • Mercy Infusion Center - Chippewa

    St Louis, Missouri, 63109, United States

  • Mercy Medical Center

    Durango, Colorado, 81301, United States

  • Mercy Medical Center - Des Moines

    Des Moines, Iowa, 50314, United States

  • Mercy Medical Center-West Lakes

    West Des Moines, Iowa, 50266, United States

  • Methodist Children's Hospital of South Texas

    San Antonio, Texas, 78229, United States

  • Midlands Community Hospital

    Papillion, Nebraska, 68046, United States

  • Miller Children's and Women's Hospital Long Beach

    Long Beach, California, 90806, United States

  • Mission Hospital

    Asheville, North Carolina, 28801, United States

  • Montefiore Medical Center - Moses Campus

    The Bronx, New York, 10467, United States

  • Montefiore Medical Center-Einstein Campus

    The Bronx, New York, 10461, United States

  • Montefiore Medical Center-Weiler Hospital

    The Bronx, New York, 10461, United States

  • Morristown Medical Center

    Morristown, New Jersey, 07960, United States

  • Mount Sinai Hospital

    New York, New York, 10029, United States

  • Mountain Blue Cancer Care Center

    Golden, Colorado, 80401, United States

  • Munson Medical Center

    Traverse City, Michigan, 49684, United States

  • NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center

    New York, New York, 10032, United States

  • NYU Langone Hospital - Long Island

    Mineola, New York, 11501, United States

  • Nationwide Children's Hospital

    Columbus, Ohio, 43205, United States

  • Naval Medical Center - Portsmouth

    Portsmouth, Virginia, 23708-2197, United States

  • Nebraska Cancer Specialists/Oncology Hematology West PC

    Grand Island, Nebraska, 68803, United States

  • Nebraska Medicine-Bellevue

    Bellevue, Nebraska, 68123, United States

  • Nebraska Medicine-Village Pointe

    Omaha, Nebraska, 68118, United States

  • Nemours Children's Clinic - Pensacola

    Pensacola, Florida, 32504, United States

  • Nemours Children's Clinic-Jacksonville

    Jacksonville, Florida, 32207, United States

  • Nemours Children's Hospital

    Orlando, Florida, 32827, United States

  • New York Medical College

    Valhalla, New York, 10595, United States

  • Newark Beth Israel Medical Center

    Newark, New Jersey, 07112, United States

  • Nicklaus Children's Hospital

    Miami, Florida, 33155, United States

  • Northwest Medical Specialties PLLC

    Tacoma, Washington, 98405, United States

  • Norton Children's Hospital

    Louisville, Kentucky, 40202, United States

  • OSF Children's Hospital of Illinois

    Peoria, Illinois, 61637, United States

  • Ochsner Medical Center Jefferson

    New Orleans, Louisiana, 70121, United States

  • Onvida Health Yuma Medical Center

    Yuma, Arizona, 85364, United States

  • Oregon Health and Science University

    Portland, Oregon, 97239, United States

  • Penn State Children's Hospital

    Hershey, Pennsylvania, 17033, United States

  • Penrose-Saint Francis Healthcare

    Colorado Springs, Colorado, 80907, United States

  • Phelps Health Delbert Day Cancer Institute

    Rolla, Missouri, 65401, United States

  • Phoenix Childrens Hospital

    Phoenix, Arizona, 85016, United States

  • Primary Children's Hospital

    Salt Lake City, Utah, 84113, United States

  • Prisma Health Richland Hospital

    Columbia, South Carolina, 29203, United States

  • ProMedica Toledo Hospital/Russell J Ebeid Children's Hospital

    Toledo, Ohio, 43606, United States

  • Providence Alaska Medical Center

    Anchorage, Alaska, 99508, United States

  • Providence Sacred Heart Medical Center and Children's Hospital

    Spokane, Washington, 99204, United States

  • Pulmonary Medicine Center of Chattanooga-Hixson

    Hixson, Tennessee, 37343, United States

  • Radiation Oncology Associates

    Reno, Nevada, 89509, United States

  • Rady Children's Hospital - San Diego

    San Diego, California, 92123, United States

  • Rainbow Babies and Childrens Hospital

    Cleveland, Ohio, 44106, United States

  • Renown Regional Medical Center

    Reno, Nevada, 89502, United States

  • Rhode Island Hospital

    Providence, Rhode Island, 02903, United States

  • Riley Hospital for Children

    Indianapolis, Indiana, 46202, United States

  • Rocky Mountain Cancer Centers - Pueblo

    Pueblo, Colorado, 81008, United States

  • Rocky Mountain Cancer Centers-Lakewood

    Lakewood, Colorado, 80228, United States

  • Rocky Mountain Cancer Centers-Longmont

    Longmont, Colorado, 80501, United States

  • Rocky Mountain Cancer Centers-Parker

    Parker, Colorado, 80138, United States

  • Rocky Mountain Cancer Centers-Penrose

    Colorado Springs, Colorado, 80907, United States

  • Rocky Mountain Cancer Centers-Thornton

    Thornton, Colorado, 80260, United States

  • Rocky Mountain Hospital for Children-Presbyterian Saint Luke's Medical Center

    Denver, Colorado, 80218, United States

  • Roswell Park Cancer Institute

    Buffalo, New York, 14263, United States

  • Rush-Copley Healthcare Center

    Yorkville, Illinois, 60560, United States

  • Rush-Copley Medical Center

    Aurora, Illinois, 60504, United States

  • Rutgers Cancer Institute of New Jersey-Robert Wood Johnson University Hospital

    New Brunswick, New Jersey, 08903, United States

  • SSM Health Good Samaritan

    Mount Vernon, Illinois, 62864, United States

  • Saint Christopher's Hospital for Children

    Philadelphia, Pennsylvania, 19134, United States

  • Saint Clare Hospital

    Lakewood, Washington, 98499, United States

  • Saint Elizabeth Hospital

    Enumclaw, Washington, 98022, United States

  • Saint Elizabeth Regional Medical Center

    Lincoln, Nebraska, 68510, United States

  • Saint Francis Cancer Center

    Greenville, South Carolina, 29607, United States

  • Saint Francis Hospital

    Greenville, South Carolina, 29601, United States

  • Saint Francis Hospital

    Federal Way, Washington, 98003, United States

  • Saint John's Hospital

    Springfield, Illinois, 62702, United States

  • Saint Joseph Medical Center Hematology and Oncology - Silverdale

    Silverdale, Washington, 98383, United States

  • Saint Joseph Radiation Oncology Resource Center

    Lexington, Kentucky, 40504, United States

  • Saint Joseph Regional Cancer Center

    Bryan, Texas, 77802, United States

  • Saint Joseph's Hospital/Children's Hospital-Tampa

    Tampa, Florida, 33607, United States

  • Saint Joseph's Regional Medical Center

    Paterson, New Jersey, 07503, United States

  • Saint Jude Children's Research Hospital

    Memphis, Tennessee, 38105, United States

  • Saint Luke's Cancer Institute - Boise

    Boise, Idaho, 83712, United States

  • Saint Mary Corwin Medical Center

    Pueblo, Colorado, 81004, United States

  • Saint Mary's Medical Center

    West Palm Beach, Florida, 33407, United States

  • Saint Mary's Regional Medical Center

    Reno, Nevada, 89503, United States

  • Saint Peter's University Hospital

    New Brunswick, New Jersey, 08901, United States

  • Saint Vincent Hospital Cancer Center Green Bay

    Green Bay, Wisconsin, 54301, United States

  • Saint Vincent Hospital Cancer Center at Marinette

    Marinette, Wisconsin, 54143, United States

  • Saints Mary and Elizabeth Hospital

    Louisville, Kentucky, 40215, United States

  • San Jorge Children's Hospital

    San Juan, 00912, Puerto Rico

  • Sanford Broadway Medical Center

    Fargo, North Dakota, 58122, United States

  • Sanford USD Medical Center - Sioux Falls

    Sioux Falls, South Dakota, 57117-5134, United States

  • Scott and White Memorial Hospital

    Temple, Texas, 76508, United States

  • Seattle Children's Hospital

    Seattle, Washington, 98105, United States

  • Sinai Hospital of Baltimore

    Baltimore, Maryland, 21215, United States

  • Southern Illinois University School of Medicine

    Springfield, Illinois, 62702, United States

  • Springfield Memorial Hospital

    Springfield, Illinois, 62781, United States

  • State University of New York Upstate Medical University

    Syracuse, New York, 13210, United States

  • Stony Brook University Medical Center

    Stony Brook, New York, 11794, United States

  • Straub Clinic and Hospital

    Honolulu, Hawaii, 96813, United States

  • Summerlin Hospital Medical Center

    Las Vegas, Nevada, 89144, United States

  • Sunrise Hospital and Medical Center

    Las Vegas, Nevada, 89109, United States

  • Sutter Medical Center Sacramento

    Sacramento, California, 95816, United States

  • T C Thompson Children's Hospital

    Chattanooga, Tennessee, 37403, United States

  • Texas Tech University Health Sciences Center-Lubbock

    Lubbock, Texas, 79430, United States

  • The Carle Foundation Hospital

    Urbana, Illinois, 61801, United States

  • The Children's Hospital at TriStar Centennial

    Nashville, Tennessee, 37203, United States

  • The Montreal Children's Hospital of the MUHC

    Montreal, Quebec, H3H 1P3, Canada

  • The Steven and Alexandra Cohen Children's Medical Center of New York

    New Hyde Park, New York, 11040, United States

  • TriHealth Cancer Institute-Anderson

    Cincinnati, Ohio, 45255, United States

  • TriHealth Cancer Institute-Westside

    Cincinnati, Ohio, 45247, United States

  • Trinity Health Grand Rapids Hospital

    Grand Rapids, Michigan, 49503, United States

  • Trinity Health Muskegon Hospital

    Muskegon, Michigan, 49444, United States

  • UCSF Benioff Children's Hospital Oakland

    Oakland, California, 94609, United States

  • UCSF Medical Center-Mission Bay

    San Francisco, California, 94158, United States

  • UCSF Medical Center-Parnassus

    San Francisco, California, 94143, United States

  • UF Health Cancer Institute - Gainesville

    Gainesville, Florida, 32610, United States

  • UI Health Care Mission Cancer and Blood - Laurel Clinic

    Des Moines, Iowa, 50314, United States

  • UI Health Care Mission Cancer and Blood - West Des Moines Clinic

    Clive, Iowa, 50325, United States

  • UMC Cancer Center / UMC Health System

    Lubbock, Texas, 79415, United States

  • UMass Memorial Medical Center - University Campus

    Worcester, Massachusetts, 01655, United States

  • UNC Lineberger Comprehensive Cancer Center

    Chapel Hill, North Carolina, 27599, United States

  • USA Health Strada Patient Care Center

    Mobile, Alabama, 36604, United States

  • UT MD Anderson Cancer Center

    Houston, Texas, 77030, United States

  • UT Southwestern/Simmons Cancer Center-Dallas

    Dallas, Texas, 75390, United States

  • University Medical Center of Southern Nevada

    Las Vegas, Nevada, 89102, United States

  • University Pediatric Hospital

    San Juan, 00926, Puerto Rico

  • University of Alberta Hospital

    Edmonton, Alberta, T6G 2B7, Canada

  • University of California Davis Comprehensive Cancer Center

    Sacramento, California, 95817, United States

  • University of Chicago Comprehensive Cancer Center

    Chicago, Illinois, 60637, United States

  • University of Illinois

    Chicago, Illinois, 60612, United States

  • University of Iowa/Holden Comprehensive Cancer Center

    Iowa City, Iowa, 52242, United States

  • University of Kentucky/Markey Cancer Center

    Lexington, Kentucky, 40536, United States

  • University of Maryland/Greenebaum Cancer Center

    Baltimore, Maryland, 21201, United States

  • University of Miami Miller School of Medicine-Sylvester Cancer Center

    Miami, Florida, 33136, United States

  • University of Michigan Rogel Cancer Center

    Ann Arbor, Michigan, 48109, United States

  • University of Minnesota/Masonic Cancer Center

    Minneapolis, Minnesota, 55455, United States

  • University of Mississippi Medical Center

    Jackson, Mississippi, 39216, United States

  • University of Missouri Children's Hospital

    Columbia, Missouri, 65212, United States

  • University of Nebraska Medical Center

    Omaha, Nebraska, 68198, United States

  • University of Oklahoma Health Sciences Center

    Oklahoma City, Oklahoma, 73104, United States

  • University of Rochester

    Rochester, New York, 14642, United States

  • University of Texas Health Science Center at San Antonio

    San Antonio, Texas, 78229, United States

  • University of Vermont Medical Center

    Burlington, Vermont, 05401, United States

  • University of Vermont and State Agricultural College

    Burlington, Vermont, 05405, United States

  • UofL Health Medical Center Northeast

    Louisville, Kentucky, 40245, United States

  • VCU Massey Comprehensive Cancer Center

    Richmond, Virginia, 23298, United States

  • Valley Children's Hospital

    Madera, California, 93636, United States

  • Vanderbilt University/Ingram Cancer Center

    Nashville, Tennessee, 37232, United States

  • Wake Forest University Health Sciences

    Winston-Salem, North Carolina, 27157, United States

  • Walter Reed National Military Medical Center

    Bethesda, Maryland, 20889-5600, United States

  • Washington University School of Medicine

    St Louis, Missouri, 63110, United States

  • Wayne State University/Karmanos Cancer Institute

    Detroit, Michigan, 48201, United States

  • West Michigan Cancer Center

    Kalamazoo, Michigan, 49007, United States

  • West Virginia University Healthcare

    Morgantown, West Virginia, 26506, United States

  • Woodland Cancer Care Center

    Michigan City, Indiana, 46360, United States

  • Yale University

    New Haven, Connecticut, 06520, United States

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