Could a tiny dose of radiation ease myeloma bone pain?
NCT ID NCT03858205
First seen Jun 08, 2026 · Last updated Jun 20, 2026 · Updated 3 times
Summary
This study tests whether a very low dose of radiation (2 Gy) can relieve bone pain in people with multiple myeloma that has spread to the bones. The goal is to see if this gentler approach works as well as standard radiation but with fewer side effects and less disruption to chemotherapy schedules. About 100 participants will report their pain levels and quality of life before and after treatment.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Cedars Sinai Medical Center
RECRUITINGLos Angeles, California, 90048, United States
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City of Hope
RECRUITINGDuarte, California, 91010, United States
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Dana-Farber Cancer Institute
RECRUITINGBoston, Massachusetts, 02215, United States
Contact
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Emory University Hospital/Winship Cancer Institute
RECRUITINGAtlanta, Georgia, 30322, United States
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Icahn School of Medicine at Mount Sinai
RECRUITINGNew York, New York, 10029, United States
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Los Angeles General Medical Center
RECRUITINGLos Angeles, California, 90033, United States
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USC / Norris Comprehensive Cancer Center
RECRUITINGLos Angeles, California, 90033, United States
Contact
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University of Minnesota - Masonic Cancer Center
RECRUITINGMinneapolis, Minnesota, 55455, United States
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University of Pennsylvania/Abramson Cancer Center
RECRUITINGPhiladelphia, Pennsylvania, 19104, United States
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Contact
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
low-dose radiation therapy
What this could lead to
If it works, this could offer a gentler, more convenient way to relieve bone pain in multiple myeloma patients, with fewer side effects and less interference with chemotherapy.
What could go wrong
This is a mid-stage trial with only 100 participants, so results may not apply to everyone. Pain relief may be modest or short-lived, and some side effects from radiation are still possible.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.