METASTATIC MALIGNANT NEOPLASM IN THE LUNG

This study compares two surgical methods to remove osteosarcoma that has spread to the lungs: open surgery (one large cut) and keyhole surgery (several small cuts with a camera). About 62 people under age 50 with up to 4 lung nodules will take part. The goal is to see which appro…

This study tests a procedure called pulmonary suffusion, which delivers chemotherapy drugs like cisplatin directly to the lungs through a minimally invasive method. The goal is to control any remaining cancer cells after surgery or ablation in patients with sarcoma or colorectal …

This study tests whether artificial intelligence can help doctors choose the right radiation dose for each person's lung tumor. About 70 adults with lung cancer or tumors that spread to the lung will receive stereotactic body radiation therapy (SBRT) with doses guided by an AI to…

This study tests a new drug called NBTXR3, which makes cancer cells more sensitive to radiation, combined with standard radiation and immunotherapy (anti-PD-1/L-1) for people with advanced solid tumors that have spread to the lungs or liver. The goal is to see if this combination…

This study tests a dye called panitumumab-IRDye800 that attaches to lung cancer cells and makes them glow under a special camera during surgery. The goal is to help surgeons see and remove all cancer tissue more accurately. About 30 adults with lung cancer or lung metastases will…

This study tests whether a CPAP machine (commonly used for sleep apnea) can reduce tumor movement in the lungs during radiation therapy for lung cancer. About 30 participants will receive stereotactic body radiation therapy (SBRT) while using either CPAP or a deep breath-holding …

This study uses robotic biopsies to collect tissue samples from people with suspected or high-risk lung cancer. The goal is to analyze the samples for genetic changes that might help diagnose cancer and build a databank for future research. About 40 adults scheduled for a standar…