Walking under the microscope: Botox's hidden effects on movement revealed
NCT ID NCT03938363
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at how cervical dystonia (neck muscle spasms) and blepharospasm (eye muscle spasms) affect walking. Researchers measured gait in 40 participants before and after botulinum toxin treatment to see if it improves walking patterns. The goal was to better understand these conditions and the treatment's impact on mobility.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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40 people
The number who actually took part.
- Started
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Oct 2019
- Finished
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Jun 2022
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * speaking French, in the ability to understand clinical tests and explorations, * in ability to move to the CHU Grenoble Alpes * Diagnosis of cervical dystonia or isolated Blepharospasm, * Absence of neurological or psychiatric disorders, * Affiliation to a health insurance, * Signed consent fo the subject. Exclusion Criteria: * Pregnant women (positive pregnancy test), parturient or breastfeeding * Cervical dystonia or Blepharospasm of secondary origin * subjects having benefited from deep brain stimulation, * History of other pathologies that may lead to walking disorders, inability to walk without technical assistance, inability to walk for more than 10 minutes, * Subjects receiving botulinum toxin treatment for another cause. Prohibited treatments and procedures: * Antecedent of pathologies that may cause walking disorders * Simultaneous participation in another Interventional study * Subject in time of exclusion from another study * Subject under guardianship or having curators (major protected) * Subject under administrative or judicial supervision * Subject not able to be contacted in case of emergency
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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CHU Grenoble Alpes
La Tronche, Isere, 38700, France
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- New pill may boost botox for stubborn neck spasms