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Could a common antidepressant supercharge cancer immunotherapy?

NCT ID NCT07174947

First seen Sep 30, 2025 · Last updated May 24, 2026 · Updated 34 times

Summary

This study tests whether adding the antidepressant fluoxetine (Prozac) to standard immunotherapy can help control tumors better in people with advanced liver or gallbladder cancer who also have depression or anxiety. About 240 participants will be randomly assigned to receive immunotherapy alone or with fluoxetine. The goal is to see if the combination improves tumor shrinkage, survival, and quality of life.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • First Affiliated Hospital of Wenzhou Medical University

    RECRUITING

    Wenzhou, Zhejiang, 325000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.