New scope technique could simplify cancer monitoring after Kidney-Sparing surgery
NCT ID NCT07557563
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This pilot study will test whether a flexible scope inserted into the urinary tract (ureterorenoscopy) under local anesthesia is safe and feasible for monitoring upper tract urothelial cancer in 10 people who have had kidney-sparing surgery. The main goal is to see if the procedure can be completed successfully, with secondary checks on complications and hospital readmission rates. If it works, it may offer a less invasive way to watch for cancer recurrence.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- flexible ureterorenoscopy (a thin, flexible scope inserted into the urinary tract to look for cancer recurrence)
- What this could lead to
- If successful, this could offer a less invasive way to monitor for cancer return after kidney-sparing surgery, potentially avoiding more frequent hospital visits or more invasive procedures.
- What could go wrong
- This is a very small pilot study with only 10 participants, so results may not apply to everyone. The procedure is done under local anesthesia, which may cause discomfort or fail, and there is a risk of complications like infection or injury.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 10 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Jun 2026
An estimate. Start dates often move.
- Expected to finish
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Mar 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Aged 18 years or older 2. Capable of giving informed consent 3. Having undergone an kidney-sparing surgery (endoscopic operation or segmental ureterectomy) Exclusion Criteria: 1. Allergy to transurethral lidocaine jelly 2. On anticoagulation or anti-platelet medication with contraindications for cessation prior to the procedure 3. Structural abnormalities in the upper urinary tract on the intended side of examination
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Prince of Wales Hospital
Hong Kong, Hong Kong
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Other studies related to the condition(s) this trial covers.
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- Could a drug combo spare bladder cancer patients from surgery?