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New fatty liver drug tested in humans for first time

NCT ID NCT05599945

First seen Nov 01, 2025 · Last updated Jun 18, 2026 · Updated 33 times

Summary

This early-stage study tested a new medicine called NNC0581-0001 in 48 adults, including healthy volunteers and people with fatty liver (hepatic steatosis). The main goal was to check safety and how the drug moves through the body after a single injection under the skin. Participants were randomly assigned to receive either the drug or a placebo. The study lasted about 58 weeks and was completed.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Parexel CPRU, Level 7

    Harrow, Middlesex, HA1 3UJ, United Kingdom

  • Parexel Research Unit

    Harrow, Middlesex, HA1 3UJ, United Kingdom

Conditions

The condition(s) this trial relates to.

fatty liver disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.